DHT Cancer Research Results

DHT, dihydrotestosterone level: Click to Expand ⟱
Source:
Type: male hormone
DHT (dihydrotestosterone) is a type of androgen, a male sex hormone, that stimulates the development of masculine characteristics such as body hair, muscle growth, and a deep voice. People who have prostate cancer usually have an increase in DHT levels.
Scientific Papers found: Click to Expand⟱
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, Nor, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, Var, NA
DHT↑, VitD↑, HDL↓,
131- CUR,    Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer
- vitro+vivo, Pca, LNCaP - vitro+vivo, Pca, 22Rv1
AKR1C2↓, CYP11A1↓, HSD3B↓, DHT↓, testos↓, StAR↓, SRD5A1↑, AR↓, tumCV↓, TumCG↓, Apoptosis↑,
8300- FS,    Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery
- Trial, Pca, NA
Dose↝, TumCP↓, Ki-67↓, *toxicity↓, Ingr↑, testos↓, DHT↓, Risk↓, Dose↝,
8415- Lyco,  CUR,    Combination of Lycopene and Curcumin Synergistically Alleviates Testosterone-Propionate-Induced Benign Prostatic Hyperplasia in Sprague Dawley Rats via Modulating Inflammation and Proliferation
- in-vivo, BPH, NA
*Dose↝, *Synergy↑, *Ki-67↓, *testos↓, *DHT↓, *PSA↓, *IL1β↓, *IL6↓, *AKT1↓, *TNF-α↓, *EGFR↓, *STAT3↓, *COX2/PTGS2↓,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

HDL↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Ki-67↓, 1,   TumCG↓, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AKR1C2↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

VitD↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CYP11A1↓, 1,   DHT↓, 2,   DHT↑, 1,   HSD3B↓, 1,   SRD5A1↑, 1,   StAR↓, 1,   testos↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Risk↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,  
Total Targets: 22

Pathway results for Effect on Normal Cells:


Kinase & Signal Transduction(tgid=6) ⓘ

AKT1↓, 1,   EGFR↓, 1,   STAT3↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Ki-67↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 1,   PSA↓, 1,   TNF-α↓, 2,   VitD↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↑, 1,   DHT↓, 1,   DHT↑, 1,   SHBG↓, 1,   testos↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   Dose↝, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   hs-CRP↓, 1,   IL6↓, 1,   PSA↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 26

Scientific Paper Hit Count for: DHT, dihydrotestosterone level
2 Boron
2 Curcumin
1 Flaxseed/Linseed
1 Lycopene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:457  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page