IL23 Cancer Research Results

IL23, Interleukin 23: Click to Expand ⟱
Source:
Type:
A heterodimeric cytokine composed of an IL-12B subunit and an IL-23A subunit. IL-23 is part of the IL-12 family of cytokines.
IL-23 is an inflammatory cytokine. IL-23 is overexpressed in a number of cancer types.
Scientific Papers found: Click to Expand⟱
3795- CUR,    Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence
- Review, AD, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *AMPK↑, *SIRT1↑, *NF-kB↓, *mTOR↓, *NLRP3↓, *NADPH↓, *ROS↓, *COX2↓, *MCP1↓, *IL1β↓, *IL17↓, *IL23↓, *TNF-α↓, *MPO↓, *IL10↑, *lipid-P↓, *SOD↑, *Aβ↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓, *TXNIP↓, *NRF2↑, *NQO1↑, *HO-1↑, *OS↑, *memory↑, *BDNF↑, *neuroP↑, *BACE↓, *AChE↓, *LDL↓,
5119- JG,    Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
- in-vivo, Nor, NA
*antiOx↑, *OS↑, *IL6↓, *IL12↓, *IL23↓, *TNF-α↓, *Inflam↓, *NF-kB↓, *NFE2L2↓, *ROS↓,
193- MFrot,  MF,    Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions
- in-vivo, Arthritis, NA
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *Aβ↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
6452- TUR,    Turmeric Essential Oil Constituents as Potential Drug Candidates: A Comprehensive Overview of Their Individual Bioactivities
- Review, Nor, NA
Dose↝, Casp3↑, MMP9↓, COX2↓, NF-kB↓, PI3K↓, Akt↓, ERK↓, Inflam↓, TNF-α↓, IL6↓, IL17↓, IL22↓, IL23↓,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

UCP1↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACAA1↓, 1,   FABP4↓, 1,   PCK1↓, 1,   PLIN1↓, 1,   PPARγ↑, 1,  

Cell Death ⓘ

Akt↓, 2,   Casp3↑, 1,  

Kinase & Signal Transduction ⓘ

Sp1/3/4↓, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   ERK↓, 2,   mTOR↓, 1,   PI3K↓, 2,   STAT3↓, 1,   Wnt↓, 1,  

Migration ⓘ

AP-1↓, 1,   Cartilage↑, 1,   COL4↓, 1,   ITGA11↓, 1,   LAMB3↑, 1,   MMP2↓, 1,   MMP9↓, 1,   THBS2↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   TumMeta↓, 1,   β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↓, 1,   COX2↓, 1,   IL17↓, 2,   IL22↓, 2,   IL23↓, 2,   IL28↓, 1,   IL6↓, 1,   Inflam↓, 1,   NF-kB↓, 2,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   Dose↝, 1,   eff↑, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   IL6↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,  

Infection & Microbiome ⓘ

CD8+↓, 1,  
Total Targets: 50

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

AntiArt↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↑, 3,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   HDL↓, 1,   HO-1↑, 2,   lipid-P↓, 2,   MDA↓, 1,   MPO↓, 1,   NFE2L2↓, 1,   NQO1↑, 1,   NRF2↑, 2,   ROS?, 1,   ROS↓, 2,   SOD↑, 1,   SOD1↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,   LDL↓, 2,   NADPH↓, 1,   SIRT1↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

Protein Folding & ER Stress ⓘ

HSP70/HSPA5↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

GSK‐3β↓, 2,   mTOR↓, 1,   STAT3↓, 1,  

Migration ⓘ

CDK5↓, 1,   MMP9↓, 1,   TXNIP↓, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IFN-γ↓, 1,   IL10↑, 1,   IL12↓, 1,   IL17↓, 2,   IL1β↓, 2,   IL23↓, 3,   IL6↓, 2,   Inflam↓, 3,   MCP1↓, 2,   NF-kB↓, 3,   TLR4↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission ⓘ

AChE↓, 2,   BDNF↑, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 2,   BACE↓, 1,   NLRP3↓, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,   IL6↓, 2,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiDiabetic↑, 1,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 2,   OS↑, 2,  

Infection & Microbiome ⓘ

AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 60

Scientific Paper Hit Count for: IL23, Interleukin 23
1 Curcumin
1 Juglone
1 Magnetic Field Rotating
1 Magnetic Fields
1 Nimbolide
1 Turmerones
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:543  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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