EPR Cancer Research Results

EPR, enhanced permeability and retention (EPR) effect: Click to Expand ⟱

Source:

Type:

Passive accumulation (in cells) is based on the unique architecture of the tumor tissue, where neo-angiogenesis leads to an atypical endothelial layer and to fenestrated vasculature, which together with the impaired lymphatic drainage guides the penetration and accumulation of nano-sized materials within the cancerous tissues.
Exploited for drug design in the nanomedicine field.

Scientific Papers found: Click to Expand⟱

5975-

AgNPs,

PDT,

CDT,

RF,

Recent Advances in the Application of Silver Nanoparticles for Enhancing Phototherapy Outcomes

Review,

Var,

Review,

BPH,

ROS↑, EPR↓, Synergy↑, Bacteria↓, eff↑, eff↑, TumVol↓,

5977-

AgNPs,

CDT,

Silver Nitroprusside as an Efficient Chemodynamic Therapeutic Agent and a Peroxynitrite nanogenerator for Targeted Cancer Therapy

in-vivo,

Ovarian,

A2780S

mouse

NA,

Ovarian,

SKOV3

Fenton↑, ROS↑, eff↑, angioG↓, p‑Akt↓, EPR↑, selectivity↑, selectivity↑, eff↑, Cyt‑c↑, HO-1↑,

4549-

AgNPs,

Silver nanoparticles: Synthesis, medical applications and biosafety

Review,

Var,

Review,

Diabetic,

ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,

4548-

AgNPs,

Chit,

Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast cancer cell lines

in-vitro,

BC,

MCF7

AntiCan↑, EPR↑, pH↝,

5146-

AgNPs,

Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent

in-vitro,

Liver,

HepG2

TumAuto↑, EPR↑, LC3B↑, CHOP/DDIT3↑, ER Stress↑, NLRP3↑, Casp1↓,

5142-

AgNPs,

Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells

in-vitro,

CRC,

HUH7

220 and 249 nm

ROS↑, Apoptosis↑, eff↑, ChemoSen↑, EPR↑, Casp↑, MAPK↑,

4403-

AgNPs,

Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment

in-vitro,

GBM,

U251

in-vitro,

GBM,

U87MG

in-vitro,

GBM,

GL26

in-vitro,

Cerv,

HeLa

in-vitro,

CRC,

RKO

AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,

4418-

AgNPs,

Nanocarriers for the topical treatment of psoriasis - pathophysiology, conventional treatments, nanotechnology, regulatory and toxicology

Human,

PSA,

*Inflam↓, *EPR↑,

4431-

AgNPs,

doxoR,

Oxidative Stress-Induced Silver Nano-Carriers for Chemotherapy

in-vitro,

BC,

4T1

PA-AgNPs have an average hydrodynamic diameter of 130 nm

in-vivo,

BC,

4T1

in-vitro,

Nor,

3T3

AntiCan↑, ROS↑, TumVol↓, EPR↑, selectivity↑, ChemoSen↑,

4438-

AgNPs,

ART/DHA,

Biogenic synthesis of AgNPs using Artemisia oliveriana extract and their biological activities for an effective treatment of lung cancer

in-vitro,

Lung,

A549

EPR↑, BAX↑, Bcl-2↑, Casp3↑, Casp9↑, DNAdam↑, TumCCA↑, Apoptosis↑,

306-

AgNPs,

Cancer Therapy by Silver Nanoparticles: Fiction or Reality?

Analysis,

Var,

EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,

5385-

AsP,

GoldNP,

GEM,

Development of ascorbyl palmitate based hydrophobic gold nanoparticles as a nanocarrier system for gemcitabine delivery

in-vitro,

BC,

 0.44 μg/mL

 The Au-GEM-
AsP-MOD

ROS↑, Fenton↑, BioAv↑, EPR↑,

5387-

AsP,

PacT,

Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy

in-vivo,

Melanoma,

B16-F10

Dose↝, TumCG↓, TumCP↓, BioAv↓, BioAv↑, other↑, Apoptosis↑, Bax:Bcl2↑, EPR↑, toxicity↝,

5543-

BBM,

Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo

in-vivo,

Lung,

B16-F10

C57BL/6 mice

vitro+vivo,

Lung,

A549

in-vitro,

BC,

MDA-MB-231

BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,

6503-

BCP,

The Potential Therapeutic Role of Beta-Caryophyllene as a Chemosensitizer and an Inhibitor of Angiogenesis in Cancer

Review,

Var,

ChemoSen↑, angioG↓, TumCI↓, TumMeta↓, ROS↑, *ROS↓, chemoP↑, CB2 / CNR2↑, Inflam↓, AntiTum↑, *BioAv↑, *BBB↑, Apoptosis↑, TumCP↑, TumCCA↑, RadioS↑, DNArepair↓, ROS↑, STAT3↓, *BioEnh↑, Pain↓, AntiBio↓, ROS↑, Dose↝, NF-kB↓, MAPK↓, TNF-α↓, IL1β↓, IL6↓, cl‑PARP↑, Casp↑, BAX↑, Bcl-2↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP2↓, p‑p38↓, p‑ERK↓, EPR↑, P-gp/ABCB1↓, MRP1/ABCC1↓, *NRF2↑, *antiOx↑,

5656-

BNL,

Role of borneol as enhancer in drug formulation: A review

Review,

Nor,

Review,

Stroke,

Review,

AD,

*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *Synergy↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, Synergy↑, other↝,

5657-

BNL,

Enhancing effect and safety assessment of borneol on the oral absorption of sub-100 nm PLGA nanoparticles

in-vivo,

Nor,

*toxicity↓, *EPR↑, *other↑,

5658-

BNL,

Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage

vitro+vivo,

GBM,

U251

 nude mice

ChemoSen↑, mt-Apoptosis↑, Casp↑, DNAdam↑, ROS↑, angioG↓, BBB↑, EPR↑, TumVol↓, TumW↓, BioEnh↑,

5660-

BNL,

Recent Progress on the Synergistic Antitumor Effect of a Borneol-Modified Nanocarrier Drug Delivery System

Review,

Var,

TumMeta↓, BBB↑, EPR↑, toxicity↓, BioAv↑, ChemoSen↑, eff↑, other↑, P-gp/ABCB1↓, MDR1↓, ROS↑, TumCCA↑, other↝, BioAv↓, DNAdam↑, BioEnh↑,

2015-

CAP,

CUR,

urea,

Anti-cancer Activity of Sustained Release Capsaicin Formulations

Review,

Var,

AntiCan↑, TumCG↓, angioG↓, TumMeta↓, BioAv↓, BioAv↓, BioAv↑, selectivity↑, EPR↑, eff↓, ChemoSen↑, Dose∅, Half-Life∅, eff↑,

5983-

Chit,

Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy

Review,

BC,

DDS↑, BioAv↑, EPR↑, TumCP↓, angioG↓, TumMeta↓, other↑,

5991-

Chit,

Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies

Review,

BC,

*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,

5995-

Chit,

CUR,

Enhancement of anticancer activity and drug delivery of chitosan-curcumin nanoparticle via molecular docking and simulation analysis

vitro+vivo,

Var,

eff↑, EPR↑, DNAdam↑, TumCCA↑, ROS↑, toxicity↓,

5994-

Chit,

Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action

Review,

Var,

angioG↓, *Imm↑, *antiOx↑, selectivity↑, other↝, toxicity↓, BioAv↑, eff↝, Half-Life↑, MPT↑, MMP9↓, lipid-P↑, EPR↑, NK cell↑, Casp3↑, Casp8↑, TumCCA↑, ROS↑, DDS↑, VEGF↓, TIMP1↑, ChemoSen↑, eff↑,

5990-

Chit,

Chitosan Nanoparticles for Targeted Cancer Therapy: A Review of Stimuli-Responsive, Passive, and Active Targeting Strategies

Review,

Var,

DDS↑, eff↓, *Bacteria↓, *antiOx↑, *Wound Healing↑, *Imm↑, TumCP↓, TumMeta↓, angioG↓, Apoptosis↑, ROS↑, ER Stress↑, BioAv↑, Half-Life↑, eff↑, EPR↑, ChemoSen↑, eff↑,

4490-

Chit,

FA,

Chitosan Nanoparticle-Based Drug Delivery Systems: Advances, Challenges, and Future Perspectives

Review,

Var,

EPR↑, *BioAv↑, *CompStab↑, *other↝, *Insulin↑, *Bacteria↓, eff↑, ChemoSen↑,

4489-

Chit,

SeNPs,

Inhibiting Metastasis and Improving Chemosensitivity via Chitosan-Coated Selenium Nanoparticles for Brain Cancer Therapy

in-vitro,

GBM,

U87MG

diameters of Cs-SeNPs with chitosan contents of 0.1, 0.15, and 0.2% were 88.66 ± 0.65, 88.90 ± 0.57, and 91.45 ± 2.57 nm

TumCG↓, TumCMig↓, TumCI↓, ChemoSen↑, *BBB↑, toxicity↓, eff↑, eff↑, selectivity↑, MMP2↓, MMP9↓, EPR↑,

4482-

Chit,

Hyaluronic acid-coated chitosan nanoparticles induce ROS-mediated tumor cell apoptosis and enhance antitumor efficiency by targeted drug delivery via CD44

in-vitro,

Lung,

A549

in-vitro,

Liver,

HepG2

EPR↑, mtDam↑, ROS↑, Apoptosis↑,

6201-

Cuc,

Cucurbitacin B and Its Derivatives: A Review of Progress in Biological Activities

Review,

Var,

Review,

AD,

*toxicity↑, *antiOx↑, *Inflam↓, *NLRP3↓, *NF-kB↓, *neuroP↑, *memory↑, *GABA↑, *cardioP↑, AntiTum↑, p‑FAK↓, ROS↑, TumMeta↑, TumCP↓, Apoptosis↑, P53↑, P21↑, TumCCA↑, p27/CDKN1B↑, CDK4↓, CDK2↓, cycD1/CCND1↓, cycE/CCNE↓, STAT3↓, ChemoSen↑, MMP2↓, MMP9↓, VEGF↓, TumCMig↓, angioG↓, NOTCH↓, EMT↓, toxicity↑, BioAv↑, EPR↑,

8846-

DIM,

ORM,

Diindolylmethane Promotes Metabolic Crisis and Enhances the Efficacy of Centchroman in Breast Cancer: A 1H NMR-Based Approach

vitro+vivo,

BC,

mouse TNBC 4T1 cells for further in vivo studies

AntiCan↑, EPR↑, Synergy↑, TumCG↓, Glycolysis↓, PKM2↓, GLUT1↓, Hif1a↓, eff↑, Glycine↓, Alanine↓, toxicity↓, Dose↝, TumW↓, Ki-67↓,

6785-

EGCG,

Epigallocatechin-3-gallate at the nanoscale: a new strategy for cancer treatment

Review,

Var,

AntiCan↑, BioAv↓, CompStab↑, EPR↑, TumCG↓, *Half-Life↝, BioAv↑, eff↑, eff↑, eff↑, NF-kB↓, ROS↑, ChemoSen↑, *toxicity↝,

6110-

EP,

Leukemic cell intracellular responses to nanosecond electric fields

in-vitro,

AML,

eff↑, EPR↑, other↝, other↝, Dose↝, Dose↝, Dose↝, eff↑,

5519-

EP,

Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions

Review,

Var,

MMP↓, Ca+2↑, Synergy↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,

6566-

Ger,

5-FU,

Geraniol, a Component of Plant Essential Oils, Sensitizes Human Colonic Cancer Cells to 5-Fluorouracil Treatment

in-vitro,

CRC,

TumCP↓, ChemoSen↑, other↝, EPR↑,

3526-

GoldNP,

Rad,

Advances in nanoparticle-based radiotherapy for cancer treatment

Review,

Var,

RadioS↑, EPR↑, ROS↑, TumCCA↑,

5390-

GoldNP,

GEM,

AsP,

Optimizing Gold Nanoparticles for Combination Therapy: Development of Hydrophobic Nanomedical Devices with Gemcitabine and Ascorbyl Palmitate

in-vitro,

BC,

4T1

EPR↑, eff↑,

7619-

HPT,

The role of hyperthermia in the treatment of tumor

Review,

Var,

Imm↑, RadioS↑, ChemoSen↑, EPR↑,

7599-

HPT,

Rad,

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome

Review,

Var,

NA↑, RadioS↑, DNArepair↓, Hypoxia↓, EPR↑, LC↑, OS↑, *toxicity↓, Dose↝, BloodF↑, pH↝, Imm↑, HSP70/HSPA5↑,

7622-

HPT,

A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers

Review,

Var,

LC↑, OS↑, QoL↑, toxicity↓, Dose↝, Dose↝, ROS↑, DNArepair↓, EPR↑, DNAdam↑, HSP70/HSPA5↑, BloodF↑, Hypoxia↓,

7687-

iod,

ESWT,

Shock Wave Application Increases the Antineoplastic Effect of Molecular Iodine Supplement in Breast Cancer Xenografts

in-vivo,

BC,

MDA-MB-231

fifty-six female athymic homozygous nude mice

antiNeop↑, CSCsMark↓, CD44↓, SOX2↓, HIF-1↓, VEGF↓, Dose↝, Dose↝, EPR↝, PPARγ↑,

8323-

LIN,

doxoR,

Efficacy of Combination Therapy with Linalool and Doxorubicin Encapsulated by Liposomes as a Two-in-One Hybrid Carrier System for Epithelial Ovarian Carcinoma

vitro+vivo,

Ovarian,

ChemoSen↑, TumCG↓, Ki-67↓, CD31/PECAM-1↓, Casp3↑, *toxicity↓, chemoP↑, *BioAv↓, EPR↑,

8321-

LIN,

doxoR,

Linalool, a plant-derived monoterpene alcohol, reverses doxorubicin resistance in human breast adenocarcinoma cells

in-vitro,

BC,

MCF7

ChemoSen↑, EPR↑, Bcl-xL↓, P-gp/ABCB1↓, TumCCA⇅, tumCV↓, Apoptosis↑,

6483-

LIN,

Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma

in-vitro,

Ovarian,

A2780S

Apoptosis↑, ROS↑, MMP↓, Casp3↑, TumW↓, ChemoSen↑, EPR↑,

8645-

MBZ,

HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo

vitro+vivo,

Colon,

CT26

BioAv↓, BioAv↑, Half-Life↑, EPR↑, AntiTum↑,

3464-

MF,

Progressive Study on the Non-thermal Effects of Magnetic Field Therapy in Oncology

Review,

Var,

AntiTum↑, TumCG↓, TumCCA↑, Apoptosis↑, TumAuto↑, Diff↑, angioG↓, TumMeta↓, EPR↑, ChemoSen↑, ROS↑, DNAdam↑, P53↑, Akt↓, MAPK↑, Casp9↑, VEGFR2/KDR/Flk1↓, P-gp/ABCB1↓,

497-

MF,

In Vitro and in Vivo Study of the Effect of Osteogenic Pulsed Electromagnetic Fields on Breast and Lung Cancer Cells

vitro+vivo,

BC,

MCF7

vitro+vivo,

Lung,

A549

TumCG↓, TumVol↓, Casp3↑, Casp7↑, Apoptosis↑, DNAdam↑, TumCCA↑, ChemoSen↑, EPR↑,

8479-

MFrot,

doxoR,

Dual-targeting by rotating magnetic field-driven superparamagnetic bionic nanorobots for enhanced triple-negative breast cancer therapy

vitro+vivo,

BC,

4T1

Dose?, EPR↑, BioEnh↑, GSH↓, GPx4↓, Iron↑, ROS↑, lipid-P↑, Ferroptosis↑, TumVol↓, Fenton↑,

7388-

MFrot,

Magnetoporation and magnetolysis of cancer cells via carbon nanotubes induced by rotating magnetic fields

in-vitro,

BC,

MCF7

EPR↑, Dose?,

8902-

MOR,

Enhanced oral bioavailability of morin administered in mixed micelle formulation with PluronicF127 and Tween80 in rats

vitro+vivo,

Nor,

To overcome the low oral bioavailability of morin, a mixed micelle formulation with pharmaceutical excipients that facilitate solubilization and modulate P-glycoprotein (P-gp) was developed and evaluated in vitro and in vivo rats.

*Dose↝, *BioAv↑, *EPR↑, *other↑, *P-gp/ABCB1↓, *other↑,

8867-

MOR,

doxoR,

Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways

in-vitro,

BC,

MDA-MB-231

ChemoSen↑, EPR↑, DNAdam↑, γH2AX↑, p‑EGFR↓, p‑STAT3↓, TumCCA↑, P21↑, cycD1/CCND1↓, FOXM1↓, tumCV↓, *p38↑,

Showing Research Papers: 1 to 50 of 53
Page 1 of 2 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 53

Pathway results for Effect on Cancer / Diseased Cells:

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 5, NRF2↑, 1, ROS↓, 2, SOD↑, 1,

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,

Core Metabolism/Glycolysis(tgid=4) ⓘ

glucose↓, 1, SIRT1↑, 1,

Cell Death(tgid=5) ⓘ

p38↑, 1,

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 3, other↝, 3,

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↑, 1, NO↓, 1,

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3, EPR↑, 4,

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↓, 1, Imm↑, 2, Inflam↓, 4, NF-kB↓, 1, NLRP3↓, 1, TNF-α↓, 1,

Synaptic & Neurotransmission(tgid=18) ⓘ

GABA↑, 1,

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2, BioAv↑, 4, BioEnh↑, 1, CompStab↑, 1, Dose↝, 1, eff↑, 2, Half-Life↝, 1, P-gp/ABCB1↓, 1, Synergy↑, 1,

Clinical Biomarkers(tgid=22) ⓘ

IL6↓, 1,

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1, AntiDiabetic↑, 1, Bone Healing↑, 1, cardioP↑, 1, memory↑, 1, neuroP↑, 2, toxicity↓, 3, toxicity↑, 1, toxicity↝, 1, Wound Healing↑, 2,

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1, AntiViral↑, 1, Bacteria↓, 5,
Total Targets: 45

Scientific Paper Hit Count for: EPR, enhanced permeability and retention (EPR) effect

11 Silver-NanoParticles
9 chitosan
5 doxorubicin
4 borneol
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Hyperthermia
3 Linalool
2 chemodynamic therapy
2 Gemcitabine (Gemzar)
2 Curcumin
2 Selenium NanoParticles
2 Electrical Pulses
2 Radiotherapy/Radiation
2 Magnetic Fields
2 Magnetic Field Rotating
2 Morin
1 Photodynamic Therapy
1 EMF
1 Artemisinin
1 Paclitaxel/Taxol
1 Berbamine
1 Beta-Caryophyllene
1 Capsaicin
1 urea
1 Folic Acid, Vit B9
1 Cucurbitacin
1 Diindolylmethane
1 Ormeloxifene (Centchroman)
1 EGCG (Epigallocatechin Gallate)
1 Geraniol
1 5-fluorouracil
1 iodine
1 Extracorporeal Shock Wave Therapy
1 mebendazole
1 Nimbolide
1 Piperlongumine

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:612  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

EPR Cancer Research Results

Pathway results for Effect on Cancer / Diseased Cells:

NA, unassigned(tgid=0) ⓘ

Redox & Oxidative Stress(tgid=1) ⓘ

Mitochondria & Bioenergetics(tgid=3) ⓘ

Core Metabolism/Glycolysis(tgid=4) ⓘ

Cell Death(tgid=5) ⓘ

Kinase & Signal Transduction(tgid=6) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

Protein Folding & ER Stress(tgid=8) ⓘ

Autophagy & Lysosomes(tgid=9) ⓘ

DNA Damage & Repair(tgid=10) ⓘ

Cell Cycle & Senescence(tgid=11) ⓘ

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Migration(tgid=13) ⓘ

Angiogenesis & Vasculature(tgid=14) ⓘ

Barriers & Transport(tgid=15) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Cellular Microenvironment(tgid=17) ⓘ

Hormonal & Nuclear Receptors(tgid=20) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Clinical Biomarkers(tgid=22) ⓘ

Functional Outcomes(tgid=23) ⓘ

Infection & Microbiome(tgid=24) ⓘ

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress(tgid=1) ⓘ

Mitochondria & Bioenergetics(tgid=3) ⓘ

Core Metabolism/Glycolysis(tgid=4) ⓘ

Cell Death(tgid=5) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

Angiogenesis & Vasculature(tgid=14) ⓘ

Barriers & Transport(tgid=15) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Synaptic & Neurotransmission(tgid=18) ⓘ

Protein Aggregation(tgid=19) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Clinical Biomarkers(tgid=22) ⓘ

Functional Outcomes(tgid=23) ⓘ

Infection & Microbiome(tgid=24) ⓘ

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