fascin Cancer Research Results

fascin, fascin: Click to Expand ⟱
Source:
Type: protein
Fascin is a protein that plays a crucial role in the regulation of cell adhesion, migration, and signaling. In the context of cancer, fascin has been found to be overexpressed in various types of tumors, including breast, lung, colon, and esophageal cancers.
Scientific Papers found: Click to Expand⟱
6462- 1,8-Cin,    Modes of Action of 1,8-Cineol in Infections and Inflammation
- Review, Var, NA - Review, AD, NA
*BioAv↑, *BBB↑, *AntiViral↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *BioAv↑, *MUC2↓, *MUC19↓, *NF-kB↓, *ICAM-1↓, *VCAM-1↓, DNAdam↑, *lipid-P↓, *PGE2↓, *IL4↓, *IL6↓, *IL1β↓, *IL6↓, eff↑, TGF-β↓, fascin↓, VEGF↓, MMP9↓, *MAPK↓, *ERK↓, JNK↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↑, *neuroP↑, *GSK‐3β↓, *AGEs↓, *BBB↑, *NLRP3↓,
469- CUR,    The inhibitory effect of curcumin via fascin suppression through JAK/STAT3 pathway on metastasis and recurrence of ovary cancer cells
- in-vitro, Ovarian, SKOV3
fascin↓, STAT3↓, JAK↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

JNK↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

GSK‐3β↑, 1,   STAT3↓, 1,   Wnt↓, 1,  

Migration ⓘ

fascin↓, 2,   MMP9↓, 1,   TGF-β↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↓, 1,  

Immune & Inflammatory Signaling ⓘ

JAK↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

MUC19↓, 1,   MUC2↓, 1,  

Redox & Oxidative Stress ⓘ

lipid-P↓, 1,  

Cell Death ⓘ

MAPK↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,   GSK‐3β↓, 1,  

Migration ⓘ

VCAM-1↓, 1,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

ICAM-1↓, 1,   IL1β↓, 1,   IL4↓, 1,   IL6↓, 2,   Inflam↓, 1,   NF-kB↓, 1,   PGE2↓, 1,  

Protein Aggregation ⓘ

AGEs↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 2,  

Clinical Biomarkers ⓘ

IL6↓, 2,  

Functional Outcomes ⓘ

neuroP↑, 1,  

Infection & Microbiome ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 23

Scientific Paper Hit Count for: fascin, fascin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:744  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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