BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
5272- 3BP,    The efficacy of the anticancer 3-bromopyruvate is potentiated by antimycin and menadione by unbalancing mitochondrial ROS production and disposal in U118 glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
Glycolysis↓, ROS↑, GPx↓, eff↓, OXPHOS↓, HK2↓, ATP↓, ROS↑, ER Stress↑, BioAv↓, Cyt‑c↑, eff↑,
5260- 3BP,    Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
- in-vivo, PC, NA
TumCG↓, toxicity↓, BioAv↝, GAPDH↓, toxicity↑, Dose↝, ATP↓, eff↑, TumCI↓, MMP9↓, toxicity↓,
3537- 5-HTP,    5-Hydroxytryptophan: a clinically-effective serotonin precursor
- Review, NA, NA
*5HT↑, *BioAv↑, *BBB↑,
5309- 5-HTP,    Effects of Carbidopa on the Cerebral Accumulation of Exogenous L-5-Hydroxytryptophan in Mice
*BioAv↑,
5298- 5-HTP,    Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa
- Human, AD, NA
*BioAv↑, *Dose↝, *toxicity↝,
5291- 5-HTP,    Kinetics of l-5-hydroxytryptophan in healthy subjects
- in-vivo, Nor, NA
*Half-Life↝, *BioAv↑,
5464- AF,    Inhibition of Thioredoxin-Reductase by Auranofin as a Pro-Oxidant Anticancer Strategy for Glioblastoma: In Vitro and In Vivo Studies
- vitro+vivo, GBM, NA
TrxR↓, BioAv↓, ROS↑, eff↝, TET1?, BioAv↑,
5457- AF,    Clinical pharmacokinetics of oral and injectable gold compounds
- Human, Nor, NA
*BioAv↝, *Dose↝, *Half-Life↑, *BioAv↝, *other↝,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
5439- AG,    Absorption enhancement study of astragaloside IV based on its transport mechanism in Caco-2 cells
- in-vitro, Colon, Caco-2
BioAv↑, BioAv↓,
4600- AgNPs,    Effects of particle size and coating on toxicologic parameters, fecal elimination kinetics and tissue distribution of acutely ingested silver nanoparticles in a mouse model
- in-vivo, Nor, NA
*Half-Life↝, *toxicity↓, *Dose↑, *other↝, *eff↝, *BioAv↓,
4598- AgNPs,    In vivo human time-exposure study of orally dosed commercial silver nanoparticles
- in-vivo, Nor, NA
*toxicity∅, *Dose↝, *Dose↝, *BioAv↝, *BioAv↝, *H2O2∅, *IL8∅, *IL1α∅, *IL1β∅, *MCP1∅, *NQO1∅, *BioAv↓,
4595- AgNPs,    ORAL DELIVERY OF SILVER NANOPARTICLES – A REVIEW
- Review, NA, NA
*BioAv↝,
4594- AgNPs,  Citrate,    Bioavailability and Toxicokinetics of citrate-coated silver nanoparticles in rats
- in-vivo, Nor, NA
*BioAv↓,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
5355- AL,    Mini-review: The health benefits and applications of allicin
- Review, Var, NA
*BioAv↑, *cardioP↑, *hepatoP↑, *RenoP↑, *Half-Life↝, *BioAv↓, *neuroP↑, *cognitive↑, *ROS↓, *lipid-P↓, *DNArepair↑, *ChemoSen↑,
2560- AL,    Effect of garlic on platelet aggregation in humans: a study in healthy subjects and patients with coronary artery disease
- ex-vivo, Nor, NA
*AntiAg↑, BioAv↝, Dose↝,
2558- AL,    Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
- Review, AD, NA
*AntiCan↑, *antiOx↑, *cardioP↑, *neuroP↑, cognitive↑, *ROS↓, *NOX↓, *TLR4↓, *NF-kB↓, *JNK↓, *AntiAg↑, *H2S↑, *BP↓, Telomerase↓, *Insulin↑, BioAv↝, *GSH↑, *Catalase↑,
2663- AL,    Therapeutic Effect of Allicin on Glioblastoma
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG
BioAv↝, TumCCA↑, P53↑, HDAC↓, CSCs↓, ROS↑, ChemoSen↑, MGMT↓,
1916- AL,    Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods
- Review, Nor, NA
*BioAv↝, *eff↓, *BioAv↝, *BioAv↝, *eff↑, *Half-Life∅, *eff↑, *eff↑, *Dose∅, *eff↑,
5165- AL,    The human allicin-proteome: S-thioallylation of proteins by the garlic defence substance allicin and its biological effects
- in-vitro, AML, Jurkat - in-vitro, Nor, L929
necrosis↑, Thiols↓, GSH↓, ENO1↓, Zn2+↑, Glycolysis↓, ATP↓, BioAv↓,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
3551- ALA,    Alpha lipoic acid treatment in late middle age improves cognitive function: Proteomic analysis of the protective mechanisms in the hippocampus
- in-vivo, AD, NA
*cognitive↑, *Apoptosis↓, *Inflam↓, *antiOx↑, *BioAv↝, *neuroP↑,
3539- ALA,    Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
- Review, AD, NA
*ROS↓, *IronCh↑, *GSH↑, *antiOx↑, *NRF2↑, *MMP9↓, *VCAM-1↓, *NF-kB↓, *cognitive↑, *Inflam↓, *BioAv↝, *BioAv↝, *BBB↑, *H2O2∅, *neuroP↑, *PKCδ↑, *ERK↑, *MAPK↑, *PI3K↑, *Akt↑, *PTEN↓, *AMPK↑, *GLUT4↑, *GlucoseCon↑, *BP↝, *eff↑, *ICAM-1↓, *VCAM-1↓, *Dose↝,
3542- ALA,    Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review
- Review, Var, NA
*antiOx↑, *VitE↑, *VitC↑, *GSH↑, *IronCh↑, *BioAv↑, *BBB↑,
3550- ALA,    Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?
- Review, AD, NA
*antiOx↑, *Inflam↓, *PGE2↓, *COX2↓, *iNOS↓, *TNF-α↓, *IL1β↓, *IL6↓, *BioAv↓, *Ach↑, *ROS↓, *cognitive↑, *neuroP↑, *BBB↑, *Half-Life↓, *BioAv↑, *Casp3↓, *Casp9↓, *ChAT↑, *cognitive↑, *eff↑, *cAMP↑, *IL2↓, *INF-γ↓, *TNF-α↓, *SIRT1↑, *SOD↑, *GPx↑, *MDA↓, *NRF2↑,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
3546- ALA,    Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study
- Study, AD, NA
*antiOx↑, *ROS↓, *cognitive∅, *lipid-P↓, *memory↑, *ChAT↑, *Acetyl-CoA↑, *Aβ↓, *BioAv↑, *BBB↑, *toxicity∅,
3545- ALA,    Potential therapeutic effects of alpha lipoic acid in memory disorders
- Review, AD, NA
*neuroP↑, *Inflam↓, *VCAM-1↓, *5HT↑, *memory↑, *BioAv↝, *Half-Life↓, *NF-kB↓, *antiOx↑, *IronCh↑, *ROS↓, *ATP↑, *ChAT↑, *Ach↑, *cognitive↑, *lipid-P↓, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *Aβ↓,
278- ALA,    The Multifaceted Role of Alpha-Lipoic Acid in Cancer Prevention, Occurrence, and Treatment
- Review, NA, NA
ROS↑, NRF2↑, Inflam↓, frataxin↑, *BioAv↓, ChemoSen↑, Hif1a↓, eff↑, FAK↓, ITGB1↓, MMP2↓, MMP9↓, EMT↓, Snail↓, Vim↓, Zeb1↓, P53↑, MGMT↓, Mcl-1↓, Bcl-xL↓, Bcl-2↓, survivin↓, Casp3↑, Casp9↑, BAX↑, p‑Akt↓, GSK‐3β↓, *antiOx↑, *ROS↓, selectivity↑, angioG↓, MMPs↓, NF-kB↓, ITGB3↓, NADPH↓,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
4132- Alum,    Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study
- Study, AD, NA
*Risk↑, *cognitive↓, *BioAv↑,
1152- Api,    Does Oral Apigenin Have Real Potential for a Therapeutic Effect in the Context of Human Gastrointestinal and Other Cancers?
- Analysis, Nor, NA
*BioAv↓, Half-Life∅, *BioAv↓, Dose∅, eff↑, CYP1A2↓, CYP2C9↓, CYP3A4↓,
1557- Api,    Preparation of apigenin nanocrystals using supercritical antisolvent process for dissolution and bioavailability enhancement
- in-vitro, Nor, NA
*BioAv↑,
1556- Api,    Dissolution and antioxidant potential of apigenin self nanoemulsifying drug delivery system (SNEDDS) for oral delivery
- Analysis, NA, NA
*BioAv↑, *Dose∅,
1554- Api,    A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota
- Review, NA, NA
*BioAv↑, *BioAv↑, *BioAv↑, *BioAv↓, *eff↑,
1551- Api,    Chemotherapeutic effects of Apigenin in breast cancer: Preclinical evidence and molecular mechanisms; enhanced bioavailability by nanoparticles
- Review, NA, NA
*BioAv↑,
1550- Api,    Formulation and characterization of an apigenin-phospholipid phytosome (APLC) for improved solubility, in vivo bioavailability, and antioxidant potential
- Analysis, NA, NA
*BioAv↑, *antiOx↑,
1548- Api,    A comprehensive view on the apigenin impact on colorectal cancer: Focusing on cellular and molecular mechanisms
- Review, Colon, NA
*BioAv↓, *Half-Life∅, selectivity↑, *toxicity↓, Wnt/(β-catenin)↓, P53↑, P21↑, PI3K↓, Akt↓, mTOR↓, TumCCA↑, TumCI↓, TumCMig↓, STAT3↓, PKM2↓, EMT↓, cl‑PARP↑, Casp3↑, Bax:Bcl2↑, VEGF↓, Hif1a↓, Dose∅, GLUT1↓, GlucoseCon↓,
1544- Api,    The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68
- in-vitro, Nor, WRL68
*SREBF2↓, *HMGCR↓, *Dose∅, *BioAv?,
1542- Api,    Bioavailability of Apigenin from Apiin-Rich Parsley in Humans
- Human, NA, NA
*BioAv?, *Half-Life?,
1540- Api,    Determination of Total Apigenin in Herbs by Micellar Electrokinetic Chromatography with UV Detection
- Analysis, NA, NA
*BioAv↑,
1538- Api,    Enhancing oral bioavailability using preparations of apigenin-loaded W/O/W emulsions: In vitro and in vivo evaluations
- in-vivo, Nor, NA
*BioAv↑,
1537- Api,    Apigenin as Tumor Suppressor in Cancers: Biotherapeutic Activity, Nanodelivery, and Mechanisms With Emphasis on Pancreatic Cancer
- Review, PC, NA
TumCP↓, TumCCA↑, Apoptosis↑, MMPs↓, Akt↓, *BioAv↑, *BioAv↓, Half-Life∅, Hif1a↓, GLUT1↓, VEGF↓, ChemoSen↑, ROS↑, Bcl-2↓, Bcl-xL↓, BAX↑, BIM↑,
1558- Api,    Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique
- in-vitro, Liver, HepG2
BioAv↑, *toxicity∅, eff↑,
2584- Api,  Chemo,    The versatility of apigenin: Especially as a chemopreventive agent for cancer
- Review, Var, NA
ChemoSen↑, RadioS↑, eff↝, DR5↑, selectivity↑, angioG↓, selectivity↑, chemoP↑, MAPK↓, PI3K↓, Akt↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, GLUT1↓, radioP↑, BioAv↓, chemoPv↑,
3822- Aroma,    Aromatherapy in the treatment of Alzheimer's disease: A systematic review
- Review, AD, NA
*cognitive↑, *other↑, *other↓, *BioAv↑, *BBB?,
3382- ART/DHA,    Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge?
- Review, Var, NA
AntiCan↑, toxicity↑, Ferroptosis↑, ROS↑, TumCCA↑, BioAv↝, eff↝, Half-Life↓, Ferritin↓, GPx4↓, NADPH↓, GSH↓, BAX↑, Cyt‑c↑, cl‑Casp3↑, VEGF↓, IL8↓, COX2↓, MMP9↓, E-cadherin↑, MMP2↓, NF-kB↓, p16↑, CDK4↓, cycD1/CCND1↓, p62↓, LC3II↑, EMT↓, CSCs↓, Wnt↓, β-catenin/ZEB1↓, uPA↓, TumAuto↑, angioG↓, ChemoSen↑,
3387- ART/DHA,    Ferroptosis: A New Research Direction of Artemisinin and Its Derivatives in Anti-Cancer Treatment
- Review, Var, NA
BioAv↓, lipid-P↑, Ferroptosis↑, Iron↑, GPx4↓, GSH↓, P53↑, ER Stress↑, PERK↑, ATF4↑, GRP78/BiP↑, CHOP↑, ROS↑, NRF2↑,

Showing Research Papers: 1 to 50 of 532
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 532

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 3,   frataxin↑, 1,   GPx↓, 1,   GPx4↓, 3,   GSH↓, 4,   Iron↑, 1,   c-Iron↑, 1,   lipid-P↑, 2,   NRF2↑, 2,   OXPHOS↓, 1,   ROS↓, 1,   ROS↑, 12,   Thiols↓, 1,   TrxR↓, 1,  

Metal & Cofactor Biology ⓘ

Ferritin↓, 1,   Zn2+↑, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 1,   ATP↓, 3,   MMP↓, 2,  

Core Metabolism/Glycolysis ⓘ

ACSL4↑, 1,   AMPK↑, 2,   CYP3A4↓, 1,   ENO1↓, 1,   FDG↓, 1,   GAPDH↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   H2S↑, 1,   HK2↓, 1,   NADPH↓, 2,   PDH↑, 2,   PKM2↓, 1,  

Cell Death ⓘ

Akt↓, 6,   p‑Akt↓, 1,   Apoptosis↑, 5,   BAX↑, 5,   Bax:Bcl2↑, 1,   Bcl-2↓, 4,   Bcl-xL↓, 2,   BIM↑, 1,   Casp↑, 2,   Casp3↑, 2,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 4,   DR5↑, 1,   Fas↑, 1,   Ferroptosis↑, 3,   MAPK↓, 2,   Mcl-1↓, 1,   necrosis↑, 1,   p27↑, 1,   survivin↓, 1,   Telomerase↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 4,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 3,   GRP78/BiP↑, 1,   PERK↑, 1,  

Autophagy & Lysosomes ⓘ

LC3II↑, 1,   p62↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   MGMT↓, 2,   p16↑, 1,   P53↑, 4,   p‑P53↑, 1,   cl‑PARP↑, 2,  

Cell Cycle & Senescence ⓘ

CDK4↓, 2,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 3,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 2,   EMT↓, 4,   GSK‐3β↓, 2,   HDAC↓, 1,   mTOR↓, 4,   NOTCH1↓, 1,   PI3K↓, 4,   STAT3↓, 1,   TumCG↓, 3,   Wnt↓, 3,   Wnt/(β-catenin)↓, 1,   Zn2+↑, 1,  

Migration ⓘ

Ca+2↑, 1,   E-cadherin↑, 1,   FAK↓, 1,   ITGB1↓, 1,   ITGB3↓, 1,   MMP2↓, 2,   MMP9↓, 3,   MMPs↓, 2,   Snail↓, 1,   TET1?, 1,   TGF-β↓, 1,   TumCI↓, 3,   TumCMig↓, 2,   TumCP↓, 4,   uPA↓, 1,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature ⓘ

angioG↓, 3,   ATF4↑, 1,   EGFR↓, 2,   EGR4↓, 1,   HIF-1↓, 1,   Hif1a↓, 3,   VEGF↓, 3,  

Barriers & Transport ⓘ

GLUT1↓, 3,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   CXCR4↓, 1,   IL12↑, 1,   IL2↑, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 1,   NF-kB↓, 3,   NF-kB↑, 1,   PD-L1↓, 1,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 7,   BioAv↑, 4,   BioAv↝, 8,   ChemoSen↑, 9,   CYP1A2↓, 1,   CYP2C9↓, 1,   Dose↓, 1,   Dose↝, 3,   Dose∅, 2,   eff↓, 1,   eff↑, 7,   eff↝, 3,   Half-Life↓, 2,   Half-Life∅, 2,   MDR1↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

EGFR↓, 2,   Ferritin↓, 1,   PD-L1↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 4,   chemoP↑, 2,   chemoPv↑, 1,   cognitive?, 1,   cognitive↑, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 1,   Remission↑, 1,   toxicity↓, 3,   toxicity↑, 2,  
Total Targets: 157

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 11,   Catalase↑, 2,   GPx↑, 2,   GSH↑, 5,   H2O2∅, 2,   lipid-P↓, 4,   MDA↓, 1,   NQO1∅, 1,   NRF2↑, 3,   ROS↓, 10,   SOD↑, 2,   VitC↑, 2,   VitE↑, 2,  

Metal & Cofactor Biology ⓘ

IronCh↑, 5,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 1,   Insulin↑, 1,  

Core Metabolism/Glycolysis ⓘ

Acetyl-CoA↑, 1,   adiP↑, 1,   AMPK↑, 1,   cAMP↑, 2,   GlucoseCon↑, 2,   H2S↑, 1,   SIRT1↑, 1,   SREBF2↓, 1,  

Cell Death ⓘ

Akt↑, 2,   Apoptosis↓, 1,   Casp3↓, 1,   Casp6↓, 1,   Casp9↓, 2,   iNOS↓, 2,   JNK↓, 2,   MAPK↑, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 3,   other↓, 2,   other↑, 1,   other↝, 5,  

DNA Damage & Repair ⓘ

DNArepair↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 2,   HMGCR↓, 1,   PI3K↑, 1,   PTEN↓, 1,  

Migration ⓘ

AntiAg↑, 2,   MMP9↓, 1,   PKCδ↑, 1,   VCAM-1↓, 3,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

BBB?, 1,   BBB↑, 6,   GLUT4↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 2,   ICAM-1↓, 1,   IL1α∅, 1,   IL1β↓, 3,   IL1β∅, 1,   IL2↓, 1,   IL6↓, 3,   IL8∅, 1,   INF-γ↓, 1,   Inflam↓, 6,   MCP1∅, 1,   NF-kB↓, 3,   p‑NF-kB↓, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 3,  

Cellular Microenvironment ⓘ

NOX↓, 1,  

Synaptic & Neurotransmission ⓘ

5HT↑, 2,   ChAT↑, 4,  

Protein Aggregation ⓘ

Aβ↓, 3,  

Drug Metabolism & Resistance ⓘ

BioAv?, 2,   BioAv↓, 12,   BioAv↑, 22,   BioAv↝, 15,   ChemoSen↑, 1,   Dose↑, 1,   Dose↝, 5,   Dose∅, 3,   eff↓, 1,   eff↑, 8,   eff↝, 1,   Half-Life?, 1,   Half-Life↓, 4,   Half-Life↑, 1,   Half-Life↝, 3,   Half-Life∅, 2,  

Clinical Biomarkers ⓘ

BP↓, 2,   BP↝, 1,   GutMicro↑, 2,   IL6↓, 3,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   cardioP↓, 1,   cardioP↑, 2,   chemoP↑, 1,   cognitive↓, 1,   cognitive↑, 8,   cognitive∅, 1,   hepatoP↑, 1,   memory↑, 5,   motorD↑, 1,   neuroP↑, 9,   RenoP↑, 1,   Risk↑, 1,   toxicity↓, 2,   toxicity↝, 1,   toxicity∅, 3,  
Total Targets: 106

Scientific Paper Hit Count for: BioAv, bioavailability
29 Curcumin
20 chitosan
18 Baicalein
17 Chlorogenic acid
16 Quercetin
16 Selenium NanoParticles
16 Sulforaphane (mainly Broccoli)
15 Apigenin (mainly Parsley)
15 Resveratrol
14 Berberine
14 EGCG (Epigallocatechin Gallate)
14 Pterostilbene
13 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Lycopene
10 Alpha-Lipoic-Acid
10 Carvacrol
9 Astaxanthin
9 borneol
9 Honokiol
9 Rosmarinic acid
8 Capsaicin
8 Chrysin
8 Piperlongumine
8 Urolithin
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Luteolin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Thymol-Thymus vulgaris
6 Propolis -bee glue
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Piperine
5 Ellagic acid
5 Fisetin
5 Magnolol
5 Naringin
5 Selenite (Sodium)
4 5-Hydroxytryptophan
4 Celastrol
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Boron
3 Caffeic acid
3 Folic Acid, Vit B9
3 Chocolate
3 Copper and Cu NanoParticles
3 Disulfiram
3 Ferulic acid
3 HydroxyTyrosol
3 Lecithin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Silicic Acid
3 Spermidine
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Chemotherapy
2 Aspirin -acetylsalicylic acid
2 Paclitaxel
2 Atorvastatin
2 immunotherapy
2 Butyrate
2 Melatonin
2 Chlorophyllin
2 Choline
2 Coenzyme Q10
2 Camptothecin
2 Emodin
2 Shilajit/Fulvic Acid
2 Gallic acid
2 Hydroxycinnamic-acid
2 magnetic nanoparticles
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Rutin
2 Selenium
2 Ursolic acid
1 Aluminum
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 doxorubicin
1 Docetaxel
1 Radiotherapy/Radiation
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 irinotecan
1 Crocetin
1 Electrical Pulses
1 Fenbendazole
1 flavonoids
1 Kaempferol
1 MCToil
1 Gambogic Acid
1 Genistein (soy isoflavone)
1 Hydrogen Gas
1 HydroxyCitric Acid
1 itraconazole
1 Methylene blue
1 Metformin
1 Magnesium
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 salinomycin
1 Date Fruit Extract
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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