T-cadherin Cancer Research Results

T-cadherin, T-cadherin/CDH13: Click to Expand ⟱
Source:
Type:
T-cadherin, also known as cadherin 13 (CDH13), is a member of the cadherin family of cell adhesion molecules.
T-cadherin is often overexpressed in certain types of cancer, including breast, prostate, and ovarian cancer. This overexpression has been associated with tumor progression, metastasis, and poor patient outcomes.
Scientific Papers found: Click to Expand⟱
806- GAR,    Garcinol exerts anti-cancer effect in human cervical cancer cells through upregulation of T-cadherin
- vitro+vivo, Pca, HeLa - vitro+vivo, Cerv, SiHa
TumCI↓, TumCMig↓, TumCCA↑, Apoptosis↑, T-cadherin↑,
7755- ISL,    Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease
- in-vivo, AD, NA
*memory↑, *p‑T-cadherin↓, *ROS↓, *ATP↑, *p‑DRP1/DNM1L↝, *MFN1↝, *MFN2↝, *neuroP↑, *cognitive↑, *mTOR↓, *ERK↓, *GSK‐3β↑,
8112- LA,    Metabolomics and proteomics reveal the inhibitory effect of Lactobacillus crispatus on cervical cancer
- in-vitro, Cerv, SiHa
HO-1↝, ACSL4↝, Ferroptosis↑, T-cadherin↑, ROS↑, lipid-P↑,
8398- LT,    Luteolin: Nature's promising warrior against Alzheimer's and Parkinson's disease
- Review, AD, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiCan↑, *hepatoP↑, *neuroP↑, *cardioP↑, *neuroG↑, *BBB↑, *ROS↓, *AChE↓, *p‑T-cadherin↓, *Aβ↓, *memory↑, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *RANTES↓, *BioAv↑, *Half-Life↝, *toxicity↓, *BACE/β-secretase↓, *Aβ42↓, *COX2/PTGS2↓, *Bcl-2↓, *Casp3↓, *BAX↓, *GSTs↓, *lipid-P↓, *Casp3↓, *Casp9↓, *memory↑, *GSK‐3β↓, *ChAT↑, *SOD↑, *GPx↑, *MDA↓, *ER Stress↓, *GRP78/BiP↓, *NRF2↑, *motorD↑, *antiAll↑,
8679- MLT,    Targeting Melatonin to Mitochondria Mitigates Castration-Resistant Prostate Cancer by Inducing Pyroptosis
- in-vitro, Pca, NA
Synergy↑, ROS↑, MMP↝, mitResp↓, T-cadherin↓, OXPHOS↓, Glycolysis↓, Pyro↑,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

HO-1↝, 1,   lipid-P↑, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mitResp↓, 1,   OXPHOS↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↝, 1,   Glycolysis↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   Ferroptosis↑, 1,   Pyro↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Migration(tgid=13) ⓘ

T-cadherin↓, 1,   T-cadherin↑, 2,   TumCI↓, 1,   TumCMig↓, 1,  

Barriers & Transport(tgid=15) ⓘ

MMP↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Synergy↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   GPx↑, 1,   GSTs↓, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

p‑DRP1/DNM1L↝, 1,   MFN1↝, 1,   MFN2↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ATP↑, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,  

Cell Death(tgid=5) ⓘ

BAX↓, 1,   Bcl-2↓, 1,   Casp3↓, 2,   Casp9↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ERK↓, 1,   mTOR↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,   GRP78/BiP↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

neuroG↑, 1,  

Migration(tgid=13) ⓘ

p‑T-cadherin↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 1,   Inflam↓, 1,   MCP1/CCL2↓, 1,   RANTES↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   ChAT↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   Aβ42↓, 1,   BACE/β-secretase↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   Half-Life↝, 1,  

Functional Outcomes(tgid=23) ⓘ

antiAll↑, 1,   AntiCan↑, 1,   cardioP↑, 1,   cognitive↑, 1,   hepatoP↑, 1,   memory↑, 3,   motorD↑, 1,   neuroP↑, 2,   toxicity↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,  
Total Targets: 48

Scientific Paper Hit Count for: T-cadherin, T-cadherin/CDH13
1 Garcinol
1 Isoliquiritigenin
1 Lactobacillus
1 Luteolin
1 Melatonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:896  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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