tbResList Print — isoFl isoflavones

Filters: qv=184, qv2=%, rfv=%

Product

isoFl isoflavones
Description: <b>Isoflavones</b> occur in many plant species, but are especially high in soybeans.<br>
Major isoflavones in soybean are genistein and daidzein<br>
Supplementation may help lower the risk of hormone-related cancers.<br>

Pathway results for Effect on Cancer / Diseased Cells

Mitochondria & Bioenergetics ⓘ

XIAP↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Casp7↑, 1,   survivin↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 1,   EMT↓, 1,  

Migration ⓘ

LEF1↓, 1,   Slug↓, 1,   Snail↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

PSA↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Clinical Biomarkers ⓘ

AR↓, 1,   PSA↓, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2010Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigenHisamitsu Ide20503397https://pubmed.ncbi.nlm.nih.gov/20503397/0
2010The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transitionSu-Ni TangPMC2933702https://pmc.ncbi.nlm.nih.gov/articles/PMC2933702/0