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Product

MFrot Magnetic Field Rotating

Description: Rotary Magnetic field can be generated by a spinning magnet or magnets. Or it can be implemented with 2 or more coils, power with a phase shift between them (90 deg for 2 coil implementation) (60deg for 3 coil implementation) 
Targets affected are mostly the same as for <a href="tbResList.php?qv=172&exPr=open">Magnet fields</a> 
Main differences 
- may enhance the EPR effect allowing targeting of drugs to cancer cells 
- acts as wireless stirrer, especially on magnetic particles(inducing eddy currents in water media) 
- research for use in nano surgery, and mechanical destruction of cancer cells 
- continue to highlight ability to raise ROS in cancer cell and lower ROS in normal cells 
- RMF may be responsible for Ca2+ distribution to pass across the plasma membrane(differental affected for cancer and normal cells) 

 
Pathways: 


- induce
<a href="tbResList.php?qv=192&tsv=275&wNotes=on">ROS</a> production in cancer cells,
while decreasing ROS in normal cells. Ca2+ is critical and the Ca2+ balance is increased in cancer
cells while decreased in normal cells (example for wound healing) 
- ROS↑ related:
<a href="tbResList.php?qv=192&tsv=197&wNotes=on&word=MMP↓">MMP↓</a>(ΔΨm),



<a href="tbResList.php?qv=192&tsv=38&wNotes=on&word=Ca+2↑">Ca+2↑</a>,
<a href="tbResList.php?qv=192&tsv=77&wNotes=on">Cyt‑c↑</a>,
<a href="tbResList.php?qv=192&wNotes=on&word=Casp">Caspases↑</a>,
<a href="tbResList.php?qv=192&tsv=82&wNotes=on&word=DNAdam↑">DNA damage↑</a>,
<a href="tbResList.php?qv=192&tsv=239&wNotes=on">cl-PARP↑</a>,
<a href="tbResList.php?qv=192&wNotes=on&word=HSP">HSP↓</a>,
<a href="tbResList.php?qv=192&wNotes=on&word=Prx">Prx</a>,

 




- Raises
<a href="tbResList.php?qv=192&tsv=1103&wNotes=on&word=antiOx↑">AntiOxidant</a>
defense in Normal Cells:
<a href="tbResList.php?qv=192&tsv=275&wNotes=on&word=ROS↓">ROS↓</a>,
<a href="tbResList.php?qv=192&tsv=226&wNotes=on&word=NRF2↑">NRF2↑</a>,
<a href="tbResList.php?qv=192&tsv=298&wNotes=on&word=SOD↑">SOD↑</a>,
<a href="tbResList.php?qv=192&tsv=137&wNotes=on&word=GSH↑">GSH↑</a>,
<a href="tbResList.php?qv=192&tsv=46&wNotes=on&word=Catalase↑">Catalase↑</a>,

 


- lowers
<a href="tbResList.php?qv=192&tsv=953&wNotes=on&word=Inflam">Inflammation</a> :
<a href="tbResList.php?qv=192&tsv=214&wNotes=on&word=NF-kB↓">NF-kB↓</a>,
<a href="tbResList.php?qv=192&tsv=66&wNotes=on&word=COX2↓">COX2↓</a>,
<a href="tbResList.php?qv=192&tsv=235&wNotes=on&word=p38↓">p38↓</a>, Pro-Inflammatory Cytokines :


<a href="tbResList.php?qv=192&tsv=309&wNotes=on&word=TNF-α↓">TNF-α↓</a>,
<a href="tbResList.php?qv=192&tsv=158&wNotes=on&word=IL6↓">IL-6↓</a>,

 


- inhibit Growth/Metastases :
<a href="tbResList.php?qv=192&tsv=604&wNotes=on">TumMeta↓</a>,
<a href="tbResList.php?qv=192&tsv=323&wNotes=on">TumCG↓</a>,

<a href="tbResList.php?qv=192&tsv=204&wNotes=on">MMPs↓</a>,
<a href="tbResList.php?qv=192&tsv=201&wNotes=on">MMP2↓</a>,
<a href="tbResList.php?qv=192&tsv=203&wNotes=on">MMP9↓</a>,

<a href="tbResList.php?qv=192&tsv=415&wNotes=on">IGF-1↓</a>,




<a href="tbResList.php?qv=192&tsv=273&wNotes=on">RhoA↓</a>,
<a href="tbResList.php?qv=192&tsv=214&wNotes=on">NF-κB↓</a>,


<a href="tbResList.php?qv=192&tsv=304&wNotes=on">TGF-β↓</a>,

<a href="tbResList.php?qv=192&tsv=105&wNotes=on">ERK↓</a>
 
 





- cause Cell cycle arrest :
<a href="tbResList.php?qv=192&tsv=322&wNotes=on">TumCCA↑</a>,





 


- inhibits Migration/Invasion :
<a href="tbResList.php?qv=192&tsv=326&wNotes=on">TumCMig↓</a>,
<a href="tbResList.php?qv=192&tsv=324&wNotes=on">TumCI↓</a>,
<a href="tbResList.php?qv=192&tsv=309&wNotes=on&word=TNF-α↓">TNF-α↓</a>, 

<a href="tbResList.php?qv=192&tsv=105&wNotes=on">ERK↓</a>,



 











- Others: <a href="tbResList.php?qv=192&tsv=252&wNotes=on">PI3K↓</a>,
<a href="tbResList.php?qv=192&tsv=4&wNotes=on">AKT↓</a>,


<a href="tbResList.php?qv=192&tsv=377&wNotes=on">Wnt↓</a>,

<a href="tbResList.php?qv=192&tsv=9&wNotes=on">AMPK</a>,

<a href="tbResList.php?qv=192&tsv=105&wNotes=on">ERK↓</a>,

<a href="tbResList.php?qv=192&tsv=168&wNotes=on">JNK</a>,

 


- Synergies:


<

<a href="tbResList.php?qv=192&tsv=961&esv=2&wNotes=on&exSp=open">Others(review target notes)</a>,
<a href="tbResList.php?qv=192&tsv=1105&wNotes=on">Neuroprotective</a>,
<a href="tbResList.php?qv=192&tsv=557&wNotes=on">Cognitive</a>,




 
 

- Selectivity:
<a href="tbResList.php?qv=192&tsv=1110&wNotes=on">Cancer Cells vs Normal Cells</a> 
 

Rotating Magnetic Fields
<table border="1" cellspacing="0" cellpadding="4">
<tr>
<th>Rank</th>
<th>Pathway / Axis</th>
<th>Cancer Cells</th>
<th>Normal Cells</th>
<th>TSF</th>
<th>Primary Effect</th>
<th>Notes / Interpretation</th>
</tr>

<tr>
<td>1</td>
<td>ROS (tumor-selective oxidative stress)</td>
<td>↑ ROS (P→R); sustained to cytotoxicity (G)</td>
<td>↔ minimal change or transient ↑ without injury (P→R)</td>
<td>P, R, G</td>
<td>Primary stress amplifier</td>
<td>Oncomagnetic reports emphasize selective tumor ROS increase with normal-cell sparing in comparable exposure conditions</td>
</tr>

<tr>
<td>2</td>
<td>Mitochondrial ETC inhibition (Complex I/NADH:ubiquinone)</td>
<td>↓ Complex I / respiration (P→R)</td>
<td>↔ limited effect (P→R)</td>
<td>P, R</td>
<td>Bioenergetic collapse trigger</td>
<td>Rotating/spinning fields are proposed to disrupt mitochondrial electron flow, driving ROS elevation upstream of ΔΨm loss</td>
</tr>

<tr>
<td>3</td>
<td>Ca²⁺ signaling (ER–mitochondria Ca²⁺ transfer / mitochondrial Ca²⁺ load)</td>
<td>↑ Ca²⁺ dysregulation (P→R) contributing to mitochondrial failure (G)</td>
<td>↔ buffered Ca²⁺ homeostasis (P→R)</td>
<td>P, R, G</td>
<td>Amplifies ETC/ROS-driven toxicity</td>
<td>RMF-driven mitochondrial stress can propagate via Ca²⁺ transfer to accelerate ΔΨm loss and pro-death ER stress in tumor cells while sparing normal cells</td>
</tr>

<tr>
<td>4</td>
<td>Mitochondrial permeability transition pore (MPTP)</td>
<td>↑ sustained MPTP opening (R→G)</td>
<td>↔ resistant to opening</td>
<td>P, R, G</td>
<td>Mitochondrial point-of-no-return</td>
<td>RMF-enhanced ROS and Ca²⁺ loading promote persistent MPTP opening in tumor mitochondria, driving energetic collapse and apoptosis while normal cells remain below the opening threshold</td>
</tr>

<tr>
<td>5</td>
<td>ΔΨm / mitochondrial membrane integrity</td>
<td>↓ ΔΨm (R); progresses (G)</td>
<td>↔ preserved</td>
<td>R, G</td>
<td>Mitochondrial failure threshold</td>
<td>Matches the “energy factory” targeting concept described in Oncomagnetic mechanism narratives</td>
</tr>

<tr>
<td>6</td>
<td>GSH depletion</td>
<td>↓ GSH (R→G)</td>
<td>↔ maintained</td>
<td>R, G</td>
<td>Loss of redox buffering</td>
<td>Cancer-selective inability to restore GSH is a key discriminator vs normal cells</td>
</tr>

<tr>
<td>7</td>
<td>NRF2 response (selectivity gate)</td>
<td>↔ delayed/insufficient NRF2 (R→G)</td>
<td>↑ NRF2 (R→G)</td>
<td>R, G</td>
<td>Adaptive protection</td>
<td>Normal-cell sparing is consistent with competent NRF2-driven antioxidant defense</td>
</tr>

<tr>
<td>8</td>
<td>ER stress / UPR (CHOP commitment)</td>
<td>↑ ER stress (R); CHOP/apoptotic UPR (G)</td>
<td>↑ adaptive UPR (R); resolves (G)</td>
<td>R, G</td>
<td>Proteostasis failure</td>
<td>ETC/ROS stress propagates to ER; commitment vs resolution diverges by cell robustness</td>
</tr>

<tr>
<td>9</td>
<td>DNA damage (oxidative; checkpoint markers)</td>
<td>↑ DNA damage (R→G)</td>
<td>↔ or repaired (G)</td>
<td>R, G</td>
<td>Checkpoint stress</td>
<td>Interpreted as ROS-mediated consequence; reported as increased damage markers in some translational datasets</td>
</tr>

<tr>
<td>10</td>
<td>LDH / glycolytic vulnerability</td>
<td>↓ LDH performance / ↓ glycolytic flux (R→G)</td>
<td>↔ metabolic flexibility</td>
<td>R, G</td>
<td>Metabolic choke</td>
<td>Cancer glycolysis becomes unstable when NADH/NAD+ and redox buffering are stressed</td>
</tr>

<tr>
<td>11</td>
<td>TrxR / thioredoxin system overload</td>
<td>↓ reserve (R→G)</td>
<td>↔ preserved</td>
<td>R, G</td>
<td>Parallel antioxidant collapse</td>
<td>Useful when GSH data are mixed; TrxR can be the limiting system under sustained ROS</td>
</tr>

</table>

<pre>
Time-Scale Flag: TSF = P / R / G
P: 0–30 min (physical / electron / radical effects)
R: 30 min–3 hr (redox signaling & stress response)
G: >3 hr (gene-regulatory adaptation)
</pre>
MPTP: opening represents a mitochondrial commitment event integrating ROS and Ca²⁺ stress; sustained opening indicates irreversible bioenergetic failure.

Research papers

Year	Title	Authors	PMID	Link
2026	Rotating magnetic field downregulating type XI collagen to suppress triple-negative breast cancer metastasis by inactivating the ITGB1/FAK/YAP signaling pathway	Tongyao Yu	—	https://www.sciencedirect.com/science/article/abs/pii/S0141813025102341
2025	Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway	Mengqing L	—	https://pubmed.ncbi.nlm.nih.gov/39461710/
2025	The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease	Annibale Antonioni	—	https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.70337?utm_source=chatgpt.com
2025	Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma	Santosh A Helekar	PMC12626803	https://pmc.ncbi.nlm.nih.gov/articles/PMC12626803/
2024	Systematic simulation of tumor cell invasion and migration in response to time-varying rotating magnetic field	Shilong Zhang	38801615	https://pubmed.ncbi.nlm.nih.gov/38801615/
2024	The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets	Elżbieta Cecerska-Heryć	PMC11012199	https://pmc.ncbi.nlm.nih.gov/articles/PMC11012199/
2024	Enhancement of chemotherapy effects by non-lethal magneto-mechanical actuation of gold-coated magnetic nanoparticles	Cristina Stavilă PhD student	—	https://www.sciencedirect.com/science/article/pii/S1549963424000352
2024	The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients: A Systematic Review	Renata Marchewka	PMC11119128	https://pmc.ncbi.nlm.nih.gov/articles/PMC11119128/
2024	Anti-tumor effect of innovative tumor treatment device OM-100 through enhancing anti-PD-1 immunotherapy in glioblastoma growth	Zhaoxian Yan	PMC11310191	https://www.nature.com/articles/s41598-024-67437-4.pdf
2024	Synergistic Effect of Chemotherapy and Magnetomechanical Actuation of Fe-Cr-Nb-B Magnetic Particles on Cancer Cells	Cristina Stavilă	PMC11256100	https://pmc.ncbi.nlm.nih.gov/articles/PMC11256100/
2024	Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice	Ruo-Wen Guo	Ruo-Wen Guo	https://pmc.ncbi.nlm.nih.gov/articles/PMC11298676/
2024	The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study	Elżbieta Cecerska-Heryć	PMC11018782	https://pmc.ncbi.nlm.nih.gov/articles/PMC11018782/
2024	Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization	Mengqing Li	PMC11493917	https://pmc.ncbi.nlm.nih.gov/articles/PMC11493917/
2024	Feature Matching of Microsecond-Pulsed Magnetic Fields Combined with Fe3O4 Particles for Killing A375 Melanoma Cells	Yan Mi	PMC11117552	https://pmc.ncbi.nlm.nih.gov/articles/PMC11117552/
2024	Gradient Rotating Magnetic Fields Impairing F-Actin-Related Gene CCDC150 to Inhibit Triple-Negative Breast Cancer Metastasis by Inactivating TGF-β1/SMAD3 Signaling Pathway	Ge Zhang	PMC10900498	https://pmc.ncbi.nlm.nih.gov/articles/PMC10900498/
2024	Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice.	Ruo-Wen Guo	—	https://ngdc.cncb.ac.cn/openlb/publication/OLB-PM-39021081
2023	Intermittent F-actin Perturbations by Magnetic Fields Inhibit Breast Cancer Metastasis	Xinmiao Ji	PMC10017101	https://pmc.ncbi.nlm.nih.gov/articles/PMC10017101/
2023	Biological effects of rotating magnetic field: A review from 1969 to 2021	Yunpeng Wei	36574882	https://pubmed.ncbi.nlm.nih.gov/36574882/
2023	Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions	Yu Han	PMC10093245	https://pmc.ncbi.nlm.nih.gov/articles/PMC10093245/
2023	Magnetically controlled cyclic microscale deformation of in vitro cancer invasion models	Daphne Osk Asgeirsson	—	https://www.researchgate.net/publication/374768956_Magnetically_Controlled_Cyclic_Microscale_Deformation_of_In_Vitro_Cancer_Invasion_Models
2023	Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes	XIAN WANG	—	https://www.science.org/doi/10.1126/sciadv.ade5321
2023	Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells	Shashank Hambarde	PMC10630398	https://pmc.ncbi.nlm.nih.gov/articles/PMC10630398/
2022	EXTH-68. ONCOMAGNETIC TREATMENT SELECTIVELY KILLS GLIOMA CANCER CELLS BY INDUCING OXIDATIVE STRESS AND DNA DAMAGE	Shashank Hambarde	PMC9661114	https://pmc.ncbi.nlm.nih.gov/articles/PMC9661114/
2022	Method and apparatus for oncomagnetic treatment	Helekar et al	—	https://patents.google.com/patent/US12186575B2/en
2022	Rotating Magnetic Field-Assisted Reactor Enhances Mechanisms of Phage Adsorption on Bacterial Cell Surface	Bartłomiej Grygorcewicz	PMC8947294	https://pmc.ncbi.nlm.nih.gov/articles/PMC8947294/
2022	Method for noninvasive whole-body stimulation with spinning oscillating magnetic fields and its safety in mice	Shashank Hambarde	36154345	https://pubmed.ncbi.nlm.nih.gov/36154345/
2021	Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device	David S Baskin	PMC8341943	https://pmc.ncbi.nlm.nih.gov/articles/PMC8341943/
2021	Magnetic fields as a potential therapy for diabetic wounds based on animal experiments and clinical trials	Huanhuan Lv	PMC7941227	https://pmc.ncbi.nlm.nih.gov/articles/PMC7941227/
2021	Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells	Martyn A Sharpe	PMC8631329	https://pmc.ncbi.nlm.nih.gov/articles/PMC8631329/
2021	Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications	Katia Varani	PMC7830993	https://pmc.ncbi.nlm.nih.gov/articles/PMC7830993/
2021	Selective induction of rapid cytotoxic effect in glioblastoma cells by oscillating magnetic fields	Santosh A Helekar	34477946	https://pubmed.ncbi.nlm.nih.gov/34477946/
2021	Magneto-mechanical destruction of cancer-associated fibroblasts using ultra-small iron oxide nanoparticles and low frequency rotating magnetic fields	Sara Lopez	PMC9417452	https://pmc.ncbi.nlm.nih.gov/articles/PMC9417452/
2021	Modulation of Cellular Response to Different Parameters of the Rotating Magnetic Field (RMF)—An In Vitro Wound Healing Study	Magdalena Jedrzejczak-Silicka	PMC8199476	https://pmc.ncbi.nlm.nih.gov/articles/PMC8199476/
2020	Synthesis of urchin-like nickel nanoparticles with enhanced rotating magnetic field-induced cell necrosis and tumor inhibition	Yong Qian	—	https://www.sciencedirect.com/science/article/abs/pii/S1385894720319513
2020	Magnetically switchable mechano-chemotherapy for enhancing the death of tumour cells by overcoming drug-resistance	Yao Chenyang	—	https://m.x-mol.net/paper/article/1307738434868318208
2020	Rotating magnetic field ameliorates experimental autoimmune encephalomyelitis by promoting T cell peripheral accumulation and regulating the balance of Treg and Th1/Th17	Tianying Zhan	PMC7185125	https://pmc.ncbi.nlm.nih.gov/articles/PMC7185125/
2020	Study on the Effect of Rotating Magnetic Field on Cellular Response of Mammalian Cells	Magdalena Jędrzejczak-Silicka	—	https://www.researchgate.net/publication/341242877_Study_on_the_Effect_of_Rotating_Magnetic_Field_on_Cellular_Response_of_Mammalian_Cells
2020	Cancer treatment by magneto-mechanical effect of particles, a review	Cécile Naud	PMC9419242	https://pmc.ncbi.nlm.nih.gov/articles/PMC9419242/
2020	The efficacy and safety of low-frequency rotating static magnetic field therapy combined with chemotherapy on advanced lung cancer patients: a randomized, double-blinded, controlled clinical trial	Minghui Zhu	32238091	https://pubmed.ncbi.nlm.nih.gov/32238091/
2019	Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans	Jiangyao Xu	—	https://www.researchgate.net/publication/337466667_Rotating_magnetic_field_delays_human_umbilical_vein_endothelial_cell_aging_and_prolongs_the_lifespan_of_Caenorhabditis_elegans
2019	Oncogenic pathways and the electron transport chain: a dangeROS liaison	Vittoria Raimondi	PMC7052168	https://pmc.ncbi.nlm.nih.gov/articles/PMC7052168/
2018	Effect of low-frequency rotary magnetic fields on advanced gastric cancer	Chen, Zheng	29970658	https://journals.lww.com/cancerjournal/fulltext/2018/14040/effect_of_low_frequency_rotary_magnetic_fields_on.15.aspx
2018	Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens	A. F. Junka	—	https://www.nature.com/articles/s41598-017-18557-7
2017	Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field	Yajing Shen	PMC5436524	https://pmc.ncbi.nlm.nih.gov/articles/PMC5436524/
2017	LF-MF inhibits iron metabolism and suppresses lung cancer through activation of P53-miR-34a-E2F1/E2F3 pathway	Jing Ren	PMC5429732	https://pmc.ncbi.nlm.nih.gov/articles/PMC5429732/
2017	Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway	Yujun Xu	PMC5603574	https://pmc.ncbi.nlm.nih.gov/articles/PMC5603574/
2016	Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT	Ruijing Tang	26807660	https://pubmed.ncbi.nlm.nih.gov/26807660/
2016	Early exposure of rotating magnetic fields promotes central nervous regeneration in planarian Girardia sinensis	Qiang Chen	27061713	https://pubmed.ncbi.nlm.nih.gov/27061713/
2016	Moderate intensity low frequency rotating magnetic field inhibits breast cancer growth in mice	Meng Zha	30142006	https://www.researchgate.net/publication/327213612_Moderate_intensity_low_frequency_rotating_magnetic_field_inhibits_breast_cancer_growth_in_mice
2015	Rotating Magnetic Field Induced Oscillation of Magnetic Particles for in vivo Mechanical Destruction of Malignant Glioma	Yu Cheng	PMC4724455	https://pmc.ncbi.nlm.nih.gov/articles/PMC4724455/
2015	Modification of bacterial cellulose through exposure to the rotating magnetic field	Karol Fijałkowski	26344254	https://pubmed.ncbi.nlm.nih.gov/26344254/
2014	Extremely low frequency magnetic fields inhibit adipogenesis of human mesenchymal stem cells	Leilei Du	25196555	https://pubmed.ncbi.nlm.nih.gov/25196555/
2013	Low Frequency Magnetic Fields Enhance Antitumor Immune Response against Mouse H22 Hepatocellular Carcinoma	Yunzhong Nie	PMC3835892	https://pmc.ncbi.nlm.nih.gov/articles/PMC3835892/
2013	Effect of low frequency magnetic fields on melanoma: tumor inhibition and immune modulation	Yunzhong Nie	PMC4029221	https://pmc.ncbi.nlm.nih.gov/articles/PMC4029221/
2012	A pilot study of extremely low-frequency magnetic fields in advanced non-small cell lung cancer: Effects on survival and palliation of general symptoms	CHENGTAO SUN	PMC3499610	https://pmc.ncbi.nlm.nih.gov/articles/PMC3499610/
2011	Involvement of midkine expression in the inhibitory effects of low-frequency magnetic fields on cancer cells	Tingting Wang	21360556	https://pubmed.ncbi.nlm.nih.gov/21360556/
2008	The hemoprotective effects of a rotary magnetic field in mice exposed to γ irradiation	Xue-jun Xie	—	https://www.semanticscholar.org/paper/The-hemoprotective-effects-of-a-rotary-magnetic-in-Xie-Qi/e39cd1191f5dc087d298977871cea29f76dec0c1
2008	The expression and intranuclear distribution of nucleolin in HL-60 and K-562 cells after repeated, short-term exposition to rotating magnetic fields	Marek Masiuk	18821389	https://pubmed.ncbi.nlm.nih.gov/18821389/
2006	Effects of 0.4 T Rotating Magnetic Field Exposure on Density, Strength, Calcium and Metabolism of Rat Thigh Bones	Xiao-yun Zhang	—	http://www.zgkjcx.com/Article/UploadFiles/200807/20080710121302169.pdf
2001	Molecular mechanism of effect of rotating constant magnetic field on organisms	X Zhang	18726401	https://pubmed.ncbi.nlm.nih.gov/18726401/
2001	The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells	Nina Mikirova, Ph.D.	—	https://isom.ca/wp-content/uploads/2020/01/JOM_2001_16_3_10_The_Effect_of_Alternating_Magnetic_Field_Exposure_and-.pdf
1999	On the mitochondrial aspect of reactive oxygen species action in external magnetic fields	P. Waliszewski	—	https://www.sciencedirect.com/science/article/abs/pii/S1011134499900003?via%3Dihub
1993	The effect of rotating magnetic fields on the growth of Deal's guinea pig sarcoma transplanted subcutaneously in guinea pigs	E Schwartz	8353767	https://pubmed.ncbi.nlm.nih.gov/8353767/
1991	The assessment of the efficacy of the effect of a rotational magnetic field on the course of the tumor process in patients with generalized breast cancer	N G Bakhmutskiĭ	—	https://pubmed.ncbi.nlm.nih.gov/1948335/
1991	The growth dynamics of Walker carcinosarcoma during exposure to a magnetic eddy field	N G Bakhmutskiĭ	1843148	https://pubmed.ncbi.nlm.nih.gov/1843148/

Year

Title

Authors

PMID

Link

Flag

2026

Rotating magnetic field downregulating type XI collagen to suppress triple-negative breast cancer metastasis by inactivating the ITGB1/FAK/YAP signaling pathway

Tongyao Yu

—

https://www.sciencedirect.com/science/article/abs/pii/S0141813025102341

2025

Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway

Mengqing L

—

https://pubmed.ncbi.nlm.nih.gov/39461710/

2025

The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease

Annibale Antonioni

—

https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.70337?utm_source=chatgpt.com

2025

Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma

Santosh A Helekar

PMC12626803

https://pmc.ncbi.nlm.nih.gov/articles/PMC12626803/

2024

Systematic simulation of tumor cell invasion and migration in response to time-varying rotating magnetic field

Shilong Zhang

38801615

https://pubmed.ncbi.nlm.nih.gov/38801615/

2024

The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets

Elżbieta Cecerska-Heryć

PMC11012199

https://pmc.ncbi.nlm.nih.gov/articles/PMC11012199/

2024

Enhancement of chemotherapy effects by non-lethal magneto-mechanical actuation of gold-coated magnetic nanoparticles

Cristina Stavilă PhD student

—

https://www.sciencedirect.com/science/article/pii/S1549963424000352

2024

The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients: A Systematic Review

Renata Marchewka

PMC11119128

https://pmc.ncbi.nlm.nih.gov/articles/PMC11119128/

2024

Anti-tumor effect of innovative tumor treatment device OM-100 through enhancing anti-PD-1 immunotherapy in glioblastoma growth

Zhaoxian Yan

PMC11310191

https://www.nature.com/articles/s41598-024-67437-4.pdf

2024

Synergistic Effect of Chemotherapy and Magnetomechanical Actuation of Fe-Cr-Nb-B Magnetic Particles on Cancer Cells

Cristina Stavilă

PMC11256100

https://pmc.ncbi.nlm.nih.gov/articles/PMC11256100/

2024

Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice

Ruo-Wen Guo

https://pmc.ncbi.nlm.nih.gov/articles/PMC11298676/

2024

The effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study

Elżbieta Cecerska-Heryć

PMC11018782

https://pmc.ncbi.nlm.nih.gov/articles/PMC11018782/

2024

Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization

Mengqing Li

PMC11493917

https://pmc.ncbi.nlm.nih.gov/articles/PMC11493917/

2024

Feature Matching of Microsecond-Pulsed Magnetic Fields Combined with Fe3O4 Particles for Killing A375 Melanoma Cells

Yan Mi

PMC11117552

https://pmc.ncbi.nlm.nih.gov/articles/PMC11117552/

2024

Gradient Rotating Magnetic Fields Impairing F-Actin-Related Gene CCDC150 to Inhibit Triple-Negative Breast Cancer Metastasis by Inactivating TGF-β1/SMAD3 Signaling Pathway

Ge Zhang

PMC10900498

https://pmc.ncbi.nlm.nih.gov/articles/PMC10900498/

2024

Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice.

Ruo-Wen Guo

—

https://ngdc.cncb.ac.cn/openlb/publication/OLB-PM-39021081

2023

Intermittent F-actin Perturbations by Magnetic Fields Inhibit Breast Cancer Metastasis

Xinmiao Ji

PMC10017101

https://pmc.ncbi.nlm.nih.gov/articles/PMC10017101/

2023

Biological effects of rotating magnetic field: A review from 1969 to 2021

Yunpeng Wei

36574882

https://pubmed.ncbi.nlm.nih.gov/36574882/

2023

Rotating Magnetic Field Mitigates Ankylosing Spondylitis Targeting Osteocytes and Chondrocytes via Ameliorating Immune Dysfunctions

Yu Han

PMC10093245

https://pmc.ncbi.nlm.nih.gov/articles/PMC10093245/

2023

Magnetically controlled cyclic microscale deformation of in vitro cancer invasion models

Daphne Osk Asgeirsson

—

https://www.researchgate.net/publication/374768956_Magnetically_Controlled_Cyclic_Microscale_Deformation_of_In_Vitro_Cancer_Invasion_Models

2023

Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes

XIAN WANG

—

https://www.science.org/doi/10.1126/sciadv.ade5321

2023

Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells

Shashank Hambarde

PMC10630398

https://pmc.ncbi.nlm.nih.gov/articles/PMC10630398/

2022

EXTH-68. ONCOMAGNETIC TREATMENT SELECTIVELY KILLS GLIOMA CANCER CELLS BY INDUCING OXIDATIVE STRESS AND DNA DAMAGE

Shashank Hambarde

PMC9661114

https://pmc.ncbi.nlm.nih.gov/articles/PMC9661114/

2022

Method and apparatus for oncomagnetic treatment

Helekar et al

—

https://patents.google.com/patent/US12186575B2/en

2022

Rotating Magnetic Field-Assisted Reactor Enhances Mechanisms of Phage Adsorption on Bacterial Cell Surface

Bartłomiej Grygorcewicz

PMC8947294

https://pmc.ncbi.nlm.nih.gov/articles/PMC8947294/

2022

Method for noninvasive whole-body stimulation with spinning oscillating magnetic fields and its safety in mice

Shashank Hambarde

36154345

https://pubmed.ncbi.nlm.nih.gov/36154345/

2021

Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device

David S Baskin

PMC8341943

https://pmc.ncbi.nlm.nih.gov/articles/PMC8341943/

2021

Magnetic fields as a potential therapy for diabetic wounds based on animal experiments and clinical trials

Huanhuan Lv

PMC7941227

https://pmc.ncbi.nlm.nih.gov/articles/PMC7941227/

2021

Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells

Martyn A Sharpe

PMC8631329

https://pmc.ncbi.nlm.nih.gov/articles/PMC8631329/

2021

Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications

Katia Varani

PMC7830993

https://pmc.ncbi.nlm.nih.gov/articles/PMC7830993/

2021

Selective induction of rapid cytotoxic effect in glioblastoma cells by oscillating magnetic fields

Santosh A Helekar

34477946

https://pubmed.ncbi.nlm.nih.gov/34477946/

2021

Magneto-mechanical destruction of cancer-associated fibroblasts using ultra-small iron oxide nanoparticles and low frequency rotating magnetic fields

Sara Lopez

PMC9417452

https://pmc.ncbi.nlm.nih.gov/articles/PMC9417452/

2021

Modulation of Cellular Response to Different Parameters of the Rotating Magnetic Field (RMF)—An In Vitro Wound Healing Study

Magdalena Jedrzejczak-Silicka

PMC8199476

https://pmc.ncbi.nlm.nih.gov/articles/PMC8199476/

2020

Synthesis of urchin-like nickel nanoparticles with enhanced rotating magnetic field-induced cell necrosis and tumor inhibition

Yong Qian

—

https://www.sciencedirect.com/science/article/abs/pii/S1385894720319513

2020

Magnetically switchable mechano-chemotherapy for enhancing the death of tumour cells by overcoming drug-resistance

Yao Chenyang

—

https://m.x-mol.net/paper/article/1307738434868318208

2020

Rotating magnetic field ameliorates experimental autoimmune encephalomyelitis by promoting T cell peripheral accumulation and regulating the balance of Treg and Th1/Th17

Tianying Zhan

PMC7185125

https://pmc.ncbi.nlm.nih.gov/articles/PMC7185125/

2020

Study on the Effect of Rotating Magnetic Field on Cellular Response of Mammalian Cells

Magdalena Jędrzejczak-Silicka

—

https://www.researchgate.net/publication/341242877_Study_on_the_Effect_of_Rotating_Magnetic_Field_on_Cellular_Response_of_Mammalian_Cells

2020

Cancer treatment by magneto-mechanical effect of particles, a review

Cécile Naud

PMC9419242

https://pmc.ncbi.nlm.nih.gov/articles/PMC9419242/

2020

The efficacy and safety of low-frequency rotating static magnetic field therapy combined with chemotherapy on advanced lung cancer patients: a randomized, double-blinded, controlled clinical trial

Minghui Zhu

32238091

https://pubmed.ncbi.nlm.nih.gov/32238091/

2019

Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans

Jiangyao Xu

—

https://www.researchgate.net/publication/337466667_Rotating_magnetic_field_delays_human_umbilical_vein_endothelial_cell_aging_and_prolongs_the_lifespan_of_Caenorhabditis_elegans

2019

Oncogenic pathways and the electron transport chain: a dangeROS liaison

Vittoria Raimondi

PMC7052168

https://pmc.ncbi.nlm.nih.gov/articles/PMC7052168/

2018

Effect of low-frequency rotary magnetic fields on advanced gastric cancer

Chen, Zheng

29970658

https://journals.lww.com/cancerjournal/fulltext/2018/14040/effect_of_low_frequency_rotary_magnetic_fields_on.15.aspx

2018

Application of Rotating Magnetic Fields Increase the Activity of Antimicrobials Against Wound Biofilm Pathogens

A. F. Junka

—

https://www.nature.com/articles/s41598-017-18557-7

2017

Elongated Nanoparticle Aggregates in Cancer Cells for Mechanical Destruction with Low Frequency Rotating Magnetic Field

Yajing Shen

PMC5436524

https://pmc.ncbi.nlm.nih.gov/articles/PMC5436524/

2017

LF-MF inhibits iron metabolism and suppresses lung cancer through activation of P53-miR-34a-E2F1/E2F3 pathway

Jing Ren

PMC5429732

https://pmc.ncbi.nlm.nih.gov/articles/PMC5429732/

2017

Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway

Yujun Xu

PMC5603574

https://pmc.ncbi.nlm.nih.gov/articles/PMC5603574/

2016

Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT

Ruijing Tang

26807660

https://pubmed.ncbi.nlm.nih.gov/26807660/

2016

Early exposure of rotating magnetic fields promotes central nervous regeneration in planarian Girardia sinensis

Qiang Chen

27061713

https://pubmed.ncbi.nlm.nih.gov/27061713/

2016

Moderate intensity low frequency rotating magnetic field inhibits breast cancer growth in mice

Meng Zha

30142006

https://www.researchgate.net/publication/327213612_Moderate_intensity_low_frequency_rotating_magnetic_field_inhibits_breast_cancer_growth_in_mice

2015

Rotating Magnetic Field Induced Oscillation of Magnetic Particles for in vivo Mechanical Destruction of Malignant Glioma

Yu Cheng

PMC4724455

https://pmc.ncbi.nlm.nih.gov/articles/PMC4724455/

2015

Modification of bacterial cellulose through exposure to the rotating magnetic field

Karol Fijałkowski

26344254

https://pubmed.ncbi.nlm.nih.gov/26344254/

2014

Extremely low frequency magnetic fields inhibit adipogenesis of human mesenchymal stem cells

Leilei Du

25196555

https://pubmed.ncbi.nlm.nih.gov/25196555/

2013

Low Frequency Magnetic Fields Enhance Antitumor Immune Response against Mouse H22 Hepatocellular Carcinoma

Yunzhong Nie

PMC3835892

https://pmc.ncbi.nlm.nih.gov/articles/PMC3835892/

2013

Effect of low frequency magnetic fields on melanoma: tumor inhibition and immune modulation

Yunzhong Nie

PMC4029221

https://pmc.ncbi.nlm.nih.gov/articles/PMC4029221/

2012

A pilot study of extremely low-frequency magnetic fields in advanced non-small cell lung cancer: Effects on survival and palliation of general symptoms

CHENGTAO SUN

PMC3499610

https://pmc.ncbi.nlm.nih.gov/articles/PMC3499610/

2011

Involvement of midkine expression in the inhibitory effects of low-frequency magnetic fields on cancer cells

Tingting Wang

21360556

https://pubmed.ncbi.nlm.nih.gov/21360556/

2008

The hemoprotective effects of a rotary magnetic field in mice exposed to γ irradiation

Xue-jun Xie

—

https://www.semanticscholar.org/paper/The-hemoprotective-effects-of-a-rotary-magnetic-in-Xie-Qi/e39cd1191f5dc087d298977871cea29f76dec0c1

2008

The expression and intranuclear distribution of nucleolin in HL-60 and K-562 cells after repeated, short-term exposition to rotating magnetic fields

Marek Masiuk

18821389

https://pubmed.ncbi.nlm.nih.gov/18821389/

2006

Effects of 0.4 T Rotating Magnetic Field Exposure on Density, Strength, Calcium and Metabolism of Rat Thigh Bones

Xiao-yun Zhang

—

http://www.zgkjcx.com/Article/UploadFiles/200807/20080710121302169.pdf

2001

Molecular mechanism of effect of rotating constant magnetic field on organisms

X Zhang

18726401

https://pubmed.ncbi.nlm.nih.gov/18726401/

2001

The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells

Nina Mikirova, Ph.D.

—

https://isom.ca/wp-content/uploads/2020/01/JOM_2001_16_3_10_The_Effect_of_Alternating_Magnetic_Field_Exposure_and-.pdf

1999

On the mitochondrial aspect of reactive oxygen species action in external magnetic fields

P. Waliszewski

—

https://www.sciencedirect.com/science/article/abs/pii/S1011134499900003?via%3Dihub

1993

The effect of rotating magnetic fields on the growth of Deal's guinea pig sarcoma transplanted subcutaneously in guinea pigs

E Schwartz

8353767

https://pubmed.ncbi.nlm.nih.gov/8353767/

1991

The assessment of the efficacy of the effect of a rotational magnetic field on the course of the tumor process in patients with generalized breast cancer

N G Bakhmutskiĭ

—

https://pubmed.ncbi.nlm.nih.gov/1948335/

1991

The growth dynamics of Walker carcinosarcoma during exposure to a magnetic eddy field

N G Bakhmutskiĭ

1843148

https://pubmed.ncbi.nlm.nih.gov/1843148/

tbResList Print — MFrot Magnetic Field Rotating

Product

Pathway results for Effect on Cancer / Diseased Cells

Redox & Oxidative Stress ⓘ

Metal & Cofactor Biology ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Transcription & Epigenetics ⓘ

Autophagy & Lysosomes ⓘ

DNA Damage & Repair ⓘ

Cell Cycle & Senescence ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Barriers & Transport ⓘ

Immune & Inflammatory Signaling ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Pathway results for Effect on Normal Cells

Redox & Oxidative Stress ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Kinase & Signal Transduction ⓘ

Transcription & Epigenetics ⓘ

Protein Folding & ER Stress ⓘ

DNA Damage & Repair ⓘ

Cell Cycle & Senescence ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Immune & Inflammatory Signaling ⓘ

Synaptic & Neurotransmission ⓘ

Protein Aggregation ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Research papers