tbResList Print — TSA Trichostatin A

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Product

TSA Trichostatin A
Description: <b>Trichostatin A (TSA)</b> is a naturally occurring compound that belongs to the class of histone deacetylase inhibitors (HDACis). <br>
TSA has been shown to induce apoptosis (programmed cell death) in various cancer cell lines, including leukemia, breast, and lung cancer cells.<br>

Pathway results for Effect on Cancer / Diseased Cells

Cell Death ⓘ

Apoptosis↑, 1,  

Transcription & Epigenetics ⓘ

ChrMod↝, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2016Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticlesNóra Igaz27434153https://pubmed.ncbi.nlm.nih.gov/27434153/0