tbResList Print — Gos Gossypol

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Product

Gos Gossypol
Description: <b>Gossypol</b> is a natural compound found in cottonseed, a byproduct of the cotton industry. It has been studied for its potential anti-cancer properties. Research has shown that gossypol can inhibit the growth of various types of cancer cells, including breast, prostate, lung, and colon cancer.<br>
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Gossypol's anti-cancer effects are thought to be due to its ability to:<br>
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-Inhibit the activity of certain enzymes involved in cancer cell growth and survival<br>
-Induce apoptosis (cell death) in cancer cells<br>
-Inhibit the formation of new blood vessels that feed cancer cells (anti-angiogenesis)<br>
-Modulate the immune system to attack cancer cells<br>
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Some studies have also suggested that gossypol may have synergistic effects when combined with other anti-cancer agents, such as chemotherapy and radiation therapy.<br>

Pathway results for Effect on Cancer / Diseased Cells

Core Metabolism/Glycolysis

lactateProd↓, 1,  

Transcription & Epigenetics

other↓, 1,  

Migration

TGF-β↓, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2018The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary FibrosisJennifer L JudgePMC5554401https://pmc.ncbi.nlm.nih.gov/articles/PMC5554401/0