Description: <b>Mushroom Shiitake</b>, Active hexose correlated compound<br>
Extracted from Basidiomycete mushrooms (eg, shiitake [Lentinula edodes]) that is purported to improve immune function.<br>
Summary:<br>
- Can significantly inhibit carcinogenesis and improve anti-tumor effects, thus increasing the effectiveness of cancer immunotherapy.<br>
- Enhanced abundance of Akkermansia in the intestine of those who responded positively to the ICI(immune checkpoint inhibitors).<br>
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-Eat fermented foods then fibre to maintain them. Fruits and vegs for fibre Chicory
root for fibre (inulin which is main prebiotic)<br>
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AHCC is mainly derived from the mycelium of Shiitake mushrooms.<br>
• It is rich in polysaccharides that are believed to enhance immune function.<br>
• The compound may influence various pathways in cancer, including boosting NK cell activity, modulating cytokine production, influencing the NF-kB inflammatory pathway, and reducing oxidative stress.<br>
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Pathways:<br>
-Stimulate cytokine production (e.g., interleukins, tumor necrosis factor) and enhance the function of macrophages and dendritic cells.<br>
<a href="https://pubmed.ncbi.nlm.nih.gov/28727820/" > https://pubmed.ncbi.nlm.nih.gov/28727820/ </a>
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