Selenate Selenate
Description: <b>Selenate</b> shares similarity with sulfate and enters cells via sulfate transporters; however, it is less readily reduced and often considered less potent in rapid cytotoxicity effects.<br>
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Selenate tends to exhibit higher IC50 values (often in the 10–100 µM range), indicating reduced potency compared to selenite in directly inducing cancer cell death.<br>
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Less Direct ROS Generation than Selenite.<br>
– Selenate’s toxicity is generally less acute because it is a more inert species until metabolically reduced.<br>
– It may exert its anticancer effects once it is converted into reduced selenium species that eventually can contribute to ROS production.<br>