tbResList Print — Brut Bruteridin

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Product

Brut Bruteridin
Description: <b>Bruteridin</b> is a lesser-known phytochemical that has been isolated from certain plant sources. Like other natural compounds with polyphenolic characteristics, bruteridin is of interest because of its potential antioxidant and anti-inflammatory activities. However, due to the limited body of research, its specific role as an anticancer agent remains largely underexplored.<br>
Typically associated with natural cardenolide mixtures from specific cardenolide-producing plants (e.g., species in the Digitalis or Adonis genera) and possibly from amphibian secretions.<br>
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-Antioxidant Activity<br>
-Anti-inflammatory Effects<br>
-Changes in histone acetylation status and chromatin remodeling can lead to altered gene expression profiles that favor tumor suppression.<br>
-Na+/K+-ATPase Inhibition<br>
-interfere with the PI3K/Akt/mTOR signaling cascade<br>
-linked to the generation of ROS within cells<br>
-Cell Cycle Arrest<br>
-Inhibition of NF-κB Signaling<br>
-alter the MAPK/ERK signaling cascade<br>

Pathway results for Effect on Cancer / Diseased Cells

Total Targets: 0

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag