AMQ Amodiaquine
Description: <b>Amodiaquine</b> is a synthetic 4-aminoquinoline compound initially developed as an antimalarial agent. Like chloroquine, it is based on the quinoline scaffold and was chemically synthesized rather than being directly extracted from natural products.<br>
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Pathways:<br>
-Autophagy Inhibition:<br>
Inhibition of autophagy and lysosomal dysfunction can lead to cellular stress through accumulation of damaged proteins and organelles, triggering pathways such as the unfolded protein response (UPR) and increasing reactive oxygen species (ROS).<br>