tbResList Print — MeJa Methyl Jasmonate

Filters: qv=294, qv2=%, rfv=%

Product

MeJa Methyl Jasmonate
Description: <b>Methyl jasmonate (MeJa)</b> is a well-known plant stress hormone. <br>
Pathways:<br>
-Causes mitochondrial dysfunction by inducing the release of cytochrome c, which leads to caspase activation.<br>
- ↓ glycolysis via hexokinase-VDAC disruption<br>
- ↑ ROS in cancer cells<br>
-MJ can lead to cell cycle arrest, thereby inhibiting the proliferation of cancer cells<br>

Pathway results for Effect on Cancer / Diseased Cells

Redox & Oxidative Stress ⓘ

H2O2?, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

toxicity↝, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2015Methyl jasmonate and its potential in cancer therapyMeng ZhangPMC4883903https://pmc.ncbi.nlm.nih.gov/articles/PMC4883903/0
2008Methyl jasmonate induces production of reactive oxygen species and alterations in mitochondrial dynamics that precede photosynthetic dysfunction and subsequent cell deathLingrui Zhang18535010https://pubmed.ncbi.nlm.nih.gov/18535010/0