tbResList Print — Xyl Xylitol

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Product

Xyl Xylitol
Description: <b>Xylitol</b> is a naturally occurring sugar alcohol commonly found in many fruits and vegetables and is often used as a low-calorie sweetener. While xylitol is best known for its dental health benefits and as a sugar substitute, there is emerging interest in its potential roles in cancer-related research.<br>
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-Xylitol may exert antioxidant effects that help reduce oxidative stress.<br>
-Xylitol is well known for its effects on oral bacteria. Since the microbiome can play a role in modulating systemic inflammation and even cancer risk, xylitol’s ability to alter microbial composition might have indirect implications for cancer risk or progression.<br>

Pathway results for Effect on Cancer / Diseased Cells

Core Metabolism/Glycolysis

PFK↓, 1,  

Migration

Ki-67↓, 1,  

Drug Metabolism & Resistance

Dose∅, 1,  

Clinical Biomarkers

Ki-67↓, 1,  

Functional Outcomes

OS↑, 1,   toxicity↓, 1,   TumVol↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2022Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral CancerYuraporn SahasakulPMC9148106https://pmc.ncbi.nlm.nih.gov/articles/PMC9148106/0