Description: <b>Triptolide</b> is a diterpenoid triepoxide primarily isolated from the traditional Chinese medicinal plant Tripterygium wilfordii Hook F (commonly known as Thunder God Vine).<br>
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Pathways:<br>
-Activation of caspases (key executioners of apoptosis)<br>
-Disruption of mitochondrial membrane potential<br>
-Cell Cycle Arrest<br>
-Suppresses expression of c-myc and mitochondrial hexokinase II (HK-II) in cancer cells<br>
Pathway results for Effect on Cancer / Diseased Cells