tbResList Print — ATO Arsenic trioxide

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Product

ATO Arsenic trioxide
Description: <b>Arsenic</b> has been known for centuries for its toxic and medicinal properties. Although once infamously used as a poison, ongoing research has repurposed arsenic derivatives for medicinal use.</br>

Pathway results for Effect on Cancer / Diseased Cells

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,  

Core Metabolism/Glycolysis ⓘ

Glycolysis↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   PGK1↓, 1,   PGM1↓, 1,  

Migration ⓘ

TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2024Vitamin C enhances the sensitivity of osteosarcoma to arsenic trioxide via inhibiting aerobic glycolysisYing Liu—https://www.sciencedirect.com/science/article/abs/pii/S0041008X230043740