tbResList Print — GABA Gamma-aminobutyric acid

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Product

GABA Gamma-aminobutyric acid
Description: <b>Gamma-aminobutyric acid (GABA)</b> is the primary inhibitory neurotransmitter in the central nervous system, and its dysregulation has been implicated in Alzheimer’s disease (AD).<br>
-Altered GABA levels: Some studies report reduced GABA levels in the brain of AD patients, while others show compensatory increases in certain brain areas.<br>
Enhancing GABAergic signaling is being explored to:<br>
-Reduce neuronal hyperexcitability.<br>
-Alleviate agitation, anxiety, and seizure-like activity in AD.<br>
-Improve memory and cognition in early disease stages.<br>
<br>
-dietary sources of GABA. They include broccoli and other cruciferous vegetables, certain peas and beans, and oat, wheat, barley, rice, tomatoes, sweet potatoes, and spinach<br>
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Pathway results for Effect on Cancer / Diseased Cells

Total Targets: 0

Pathway results for Effect on Normal Cells

Transcription & Epigenetics

other↓, 1,  

Functional Outcomes

Sleep∅, 1,  
Total Targets: 2

Research papers

Year Title Authors PMID Link Flag
2020Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic ReviewPiril HepsomaliPMC7527439https://pmc.ncbi.nlm.nih.gov/articles/PMC7527439/0
2015Treatment Options in Alzheimer´s Disease: The GABA StoryMaite Solas26365140https://pubmed.ncbi.nlm.nih.gov/26365140/0