SAMe S-adenosyl-L-methionine
Description: <b>S-adenosyl-L-methionine (SAMe)<b> is a naturally occurring compound involved in methylation, transsulfuration, and aminopropylation pathways. It has been studied for its potential therapeutic effects in various diseases, including cancer and Alzheimer’s disease (AD).<br>
- B-12 and folic acid to help facilitate the effects of SAMe<br>
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-In AD, hypomethylation of certain genes (e.g. APP, BACE1) leads to increased amyloid-β production. SAMe supplementation may reverse this.<br>
-SAMe is a cofactor in the synthesis of dopamine, serotonin, and norepinephrine, which are often deficient in AD and depression.<br>
-Studies in AD animal models show improved cognitive function, reduced amyloid plaque formation, and restored methylation patterns<br>
-Some human data support cognitive improvement when combined with B vitamins and folate, especially in early or mild cognitive impairment.<br>
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Cancer:<br>
-Tumor suppessive in some cancers, pro-tumor risks in others.