tbResList Print — 5HT Serotonin, 5-hydroxytryptamine

Filters: qv=353, qv2=%, rfv=%

Product

5HT Serotonin, 5-hydroxytryptamine
Description: <b>5-HT (5-hydroxytryptamine), commonly known as serotonin</b>, plays a significant role in Alzheimer’s disease (AD). Its dysfunction is associated with both the cognitive and neuropsychiatric symptoms of AD.<br>
-Serotonin is a neurotransmitter involved in: Mood regulation, Sleep, Cognition, Appetite<br>
-Decreased serotonin levels are seen in the brains of AD patients.<br>
-Serotonin may reduce Aβ production via certain receptor pathways (e.g., 5-HT4 activation).<br>
<pre>
Natural Serotonin Enhancers
-5-HTP Direct precursor to serotonin
-Curcumin MAO-A inhibitor (prevent serotonin breakdown)
-Resveratrol Inhibits MAO (prevent serotonin breakdown)
-Tryptophan Amino acid precursor to serotonin
-Saffron (crocin) Inhibits serotonin reuptake ↑ Synaptic 5-HT
-Green tea (L-theanine)
-Ginkgo biloba
-Omega-3 fatty acids Enhances serotonin release
-Vitamin B6, B12, Folate Cofactors in serotonin synthesis
</pre>

Pathway results for Effect on Cancer / Diseased Cells

Total Targets: 0

Pathway results for Effect on Normal Cells

Transcription & Epigenetics

other↑, 1,   other↓, 1,  

Drug Metabolism & Resistance

eff↑, 2,  

Functional Outcomes

cognitive↑, 2,  
Total Targets: 4

Research papers

Year Title Authors PMID Link Flag
2018Nutrition strategies that improve cognitive functionRosa María Martínez García30351155https://pubmed.ncbi.nlm.nih.gov/30351155/0
2011Role of serotonin in Alzheimer's disease: a new therapeutic target?Werner J Geldenhuys21870888https://pubmed.ncbi.nlm.nih.gov/21870888/0