tbResList Print — Anzaroot Anzaroot, Astragalus fasciculifolius Bioss

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Product

Anzaroot Anzaroot, Astragalus fasciculifolius Bioss
Description: <b>Anzaroot<b>, Astragalus fasciculifolius Bioss : (the traditional gum/resin from Astragalus sarcocolla, also written “sarcocolla” or “sarcocolla gum”) is a complex natural product whose main bioactive classes are — polysaccharides (gum carbohydrates), flavonoids/phenolics, and triterpene saponins (including astragaloside-type saponins in the broader Astragalus genus <br>
-extracts or Anzaroot-mediated silver nanoparticles have shown cytotoxic effects on cancer cell lines; the proposed anticancer mechanisms are apoptosis induction, ROS generation, cell-cycle arrest and immunomodulation via NF-κB / PI3K-Akt / MAPK and caspase pathways.<br>



Pathway results for Effect on Cancer / Diseased Cells

Redox & Oxidative Stress

ROS↑, 1,  

DNA Damage & Repair

P53↑, 1,  

Proliferation, Differentiation & Cell State

TumCG↓, 1,  

Barriers & Transport

CellMemb↑, 1,  

Drug Metabolism & Resistance

eff↑, 1,   selectivity↑, 1,  

Functional Outcomes

chemoP↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2025Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cellsFatemeh NosratiPMC12264097https://pmc.ncbi.nlm.nih.gov/articles/PMC12264097/0