tbResList Print — Neem Neem

Filters: qv=420, qv2=%, rfv=%

Product

Neem Neem
Description: <p><strong>Neem</strong> (<em>Azadirachta indica</em>) is a medicinal plant whose
leaves, bark, seeds, and oil contain multiple bioactive compounds, including
nimbolide, nimbidin, azadirachtin, gedunin, and quercetin. Reported activities
include antimicrobial, antifungal, antiparasitic, anti-inflammatory, and
anticancer effects. Neem is entered separately from nimbolide because
neem extracts are complex mixtures, while nimbolide is a single isolated
limonoid.
<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4791507/">Reference</a>
</p>

Pathway results for Effect on Cancer / Diseased Cells

Mitochondria & Bioenergetics(tgid=3) ⓘ

XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   BAX↓, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 1,   survivin↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PI3K↓, 1,   PTEN↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

NF-kB↓, 1,  
Total Targets: 15

Pathway results for Effect on Normal Cells

NA, unassigned(tgid=0) ⓘ

AntiBio↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Migration(tgid=13) ⓘ

5LO↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   Imm↑, 1,   Inflam↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↑, 1,  
Total Targets: 13

Research papers

Year Title Authors PMID Link Flag
2022The Antimicrobial Potential of the Neem Tree Azadirachta indicaMarina R WyliePMC9195866https://pmc.ncbi.nlm.nih.gov/articles/PMC9195866/0
2016Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and TreatmentMohammad A AlzohairyPMC4791507https://pmc.ncbi.nlm.nih.gov/articles/PMC4791507/0