Description: <p>
<strong>Tetrahydroxystilbene glucoside (TSG; 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside)</strong>
is an isolated stilbene glycoside and a major bioactive constituent of
<em>Polygonum multiflorum</em> Thunb. TSG has antioxidant, anti-inflammatory,
mitochondrial-protective, neuroprotective and cardiovascular effects in
preclinical studies. In Alzheimer-related models, it has reduced amyloid-β
toxicity and microglial activation, supported synaptic plasticity, protected
against mitochondrial dysfunction and improved learning or memory outcomes.
Alternative names include THSG, PM-SG and tetrahydroxystilbene glucoside.
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