tbResList Print — CAR Carvacrol

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Product

CAR Carvacrol
Description: <b>Carvacrol</b> monoterpenoid phenol with odor of oregano. Found in essential oils and plants, has antimicorbial and antioxidant properties.<br>

Pathway results for Effect on Cancer / Diseased Cells

Core Metabolism/Glycolysis ⓘ

PPARα↑, 1,   PPARγ↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Cyt‑c↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

PI3K↓, 1,  

Migration ⓘ

COL1↓, 1,   COL4↓, 1,   E-cadherin↑, 1,   Fibronectin↓, 1,   Snail↑, 1,   TumCP↓, 1,   Vim↑, 1,   α-SMA↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2022Carvacrol induces apoptosis in human breast cancer cells via Bcl-2/CytC signaling pathwayHu-hu Chen—https://www.researchgate.net/publication/364049199_Carvacrol_induces_apoptosis_in_human_breast_cancer_cells_via_Bcl-2CytC_signaling_pathway0
2021Carvacrol Ameliorates Transforming Growth Factor-β1-Induced Extracellular Matrix Deposition and Reduces Epithelial-Mesenchymal Transition by Regulating The Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway In Hk-2 CellsYunhe Gu—https://www.researchgate.net/publication/352254681_Carvacrol_Ameliorates_Transforming_Growth_Factor-b1-Induced_Extracellular_Matrix_Deposition_and_Reduces_Epithelial-Mesenchymal_Transition_by_Regulating_The_Phosphatidylinositol_3-KinaseProtein_Kinase_0
2010Carvacrol, a component of thyme oil, activates PPARα and γ and suppresses COX-2 expressionMariko HottaPMC2789773https://pmc.ncbi.nlm.nih.gov/articles/PMC2789773/0