bemp bempedoic acid
Description: <b>Bempedoic acid></b> is a synthetic small‐molecule drug developed to lower low‐density lipoprotein cholesterol (LDL-C) by targeting lipid metabolism in the liver. Its design and development were based on a detailed understanding of cholesterol biosynthetic pathways rather than on a natural product scaffold.<br>
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Key Pathways:<br>
-ATP Citrate Lyase (ACLY) Inhibition<br>
-Fatty Acid Synthesis and Lipogenesis<br>
• With reduced acetyl-CoA, de novo fatty acid synthesis is also curtailed.<br>