tbResList Print — CP Cyclopamine

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Product

CP Cyclopamine
Description: <b>Cyclopamine</b> is a natural steroidal alkaloid derived from the corn lily, Veratrum californicum, which specifically disrupts the Hh signaling pathway.<br>

Pathway results for Effect on Cancer / Diseased Cells

Proliferation, Differentiation & Cell State

EMT↓, 1,   Gli1↓, 1,   HH↓, 1,  

Migration

E-cadherin↑, 1,   N-cadherin↓, 1,   Snail↓, 1,   TumCI↓, 1,   TumMeta↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2015Resveratrol inhibits the hedgehog signaling pathway and epithelial-mesenchymal transition and suppresses gastric cancer invasion and metastasisQian Gao26137075https://pubmed.ncbi.nlm.nih.gov/26137075/0