tbResList Print — CBC/D Cynanbungeigenin C (CBC) and D (CBD)

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Product

CBC/D Cynanbungeigenin C (CBC) and D (CBD)
Description: <b>Cynanbungeigenin C (CBC) and D (CBD)</b> from the plant Cynanchum bungei Decne <br>

Pathway results for Effect on Cancer / Diseased Cells

Proliferation, Differentiation & Cell State ⓘ

Gli1↓, 2,   HH↓, 2,  

Migration ⓘ

TumCP↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells

Total Targets: 0

Research papers

Year Title Authors PMID Link Flag
2024CBC-1 as a Cynanbungeigenin C derivative inhibits the growth of colorectal cancer through targeting Hedgehog pathway component GLI 1Chen, Jinwen—https://www.ovid.com/journals/steri/abstract/10.1016/j.steroids.2024.109421~b-classlwwarticleemphasis-lwwarticleemphasisboldcbc1-as-a0
2023Cynanbungeigenin C and D, a pair of novel epimers from Cynanchum bungei, suppress hedgehog pathway-dependent medulloblastoma by blocking signaling at the level of Gli—https://www.sciencedirect.com/science/article/abs/pii/S0304383518301307?via%3Dihub0