ABL1 is a protein tyrosine kinase involved in cell differentiation, division and stress response.
ABL1 (Abelson murine leukemia viral oncogene homolog 1) is a gene that encodes a protein tyrosine kinase, which plays a crucial role in various cellular processes, including cell division, differentiation, and response to stress.
ABL1, its role as an oncogene is most prominently illustrated by the BCR-ABL fusion protein, which is formed through a chromosomal translocation between the ABL1 gene and the BCR gene.
High ABL1 Expression: In some cancers, high levels of ABL1 expression may correlate with poor prognosis, while in others, it may not have a significant impact.
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