CYP2E1 is an enzyme belonging to the cytochrome P450 family that is primarily involved in the metabolism of small organic molecules, including drugs, toxins, and endogenous substrates. It plays a significant role in the biotransformation of various compounds through oxidation reactions.
Due to its role in metabolizing procarcinogenic compounds, elevated CYP2E1 activity has been linked to an increased risk of certain cancers, particularly in the context of chronic alcohol consumption or exposure to environmental toxins. In some studies, higher CYP2E1 levels have been associated with liver cancer and may also influence risk in other tissues.
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