While many studies suggest that altered SSBP1 expression is linked to tumor aggressiveness and patient outcomes, the direction of change (upregulation or downregulation) and the prognostic implications can vary between cancer types. For instance:
• In breast and colorectal cancers, lower SSBP1 expression has been associated with enhanced invasiveness and poorer prognosis.
• In lung cancer, higher SSBP1 expression in some studies correlates with more aggressive disease features and unfavorable outcomes.
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