Annexin II belongs to the annexin family that binds phospholipids in a calcium-dependent manner.
– Elevated levels of Annexin II have been implicated in cancer cell invasion, migration, and metastasis.
– High Annexin II expression is frequently associated with aggressive tumor behavior, including increased invasion, metastasis, and overall poor clinical outcomes.
Annexin II is a significant contributor to cancer progression through its roles in cell invasion, extracellular matrix degradation, and angiogenesis. Its overexpression is frequently correlated with aggressive tumor behavior and poor prognosis, making it a promising candidate for both prognostic evaluation and as a therapeutic target.
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