Keratin 17 (K17) is an intermediate filament protein that has emerged as more than just a structural component in epithelial cells.
-K17 is frequently upregulated in certain subtypes of breast, CC, SCC cancer, especially in triple-negative breast cancers (TNBC).
–Prognosis: High K17 expression has been correlated with aggressive tumor behavior, higher proliferation rates, and poorer overall survival. It is emerging as a marker for tumor aggressiveness in this context.
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