β-Endorphin is an endogenous opioid peptide produced through the cleavage of proopiomelanocortin (POMC) primarily in the anterior pituitary.
– It is well known for its roles in pain relief, stress reduction, and modulation of the immune system.
– β-Endorphin can interact with opioid receptors expressed in various tissues, including cells within the tumor microenvironment.
– Some studies indicate that increased β-endorphin or POMC expression might correlate with altered stress responses in cancer patients, which could indirectly influence survival outcomes.
- In specific contexts, higher β-endorphin levels might be associated with improved pain control and quality of life, which could reflect in better overall outcomes.
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