CoQ10 (coenzyme Q10) is most widely recognized for its role in mitochondrial bioenergetics and antioxidant defense.
CoQ10 is a key coenzyme for ATP generation that primarily transfers electron from CI and complex II (CII) to CIII in mitochondrial ETC
-It functions as a potent antioxidant, protecting cells from oxidative damage and lipid peroxidation.
-Some studies have suggested that low circulating CoQ10 levels in cancer patients (for example, in breast or colorectal cancer) might be associated with more aggressive disease or poorer overall health status.
-Deficiency of NADH dehydrogenase ubiquinone 1 subunit (Ndufc2), a subunit of CI, has been found in diabetes, cancer, and stroke
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