Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich proteins known primarily for their ability to bind heavy metals such as zinc, copper, cadmium, and mercury.
-Owing to their high cysteine content, metallothioneins can scavenge reactive oxygen species (ROS) and mitigate oxidative stress.
-Studies have investigated how inducing metallothionein expression (through dietary or pharmacological means) could offer a protective effect against carcinogens.
-Metallothioneins play a significant role in cellular protection mechanisms tied to detoxification and antioxidant defense, which are key elements of chemoprevention.
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