GPX8, or Glutathione Peroxidase 8, is a member of the glutathione peroxidase family of enzymes, which play a crucial role in protecting cells from oxidative stress by reducing hydrogen peroxide and other peroxides.
Glutathione peroxidase 8 (GPX8) is a member of the glutathione peroxidase family, which plays a role in protecting cells from oxidative stress by reducing hydrogen peroxide and organic peroxides. GPX8 is unique among the GPX family as it is primarily localized in the endoplasmic reticulum (ER) and is involved in maintaining redox homeostasis within this organelle.
GPX8 is involved in the cellular response to oxidative stress, and its expression can be altered in various cancers. While some studies suggest that increased GPX8 levels may correlate with tumor aggressiveness and resistance to oxidative stress, the specific prognostic implications of GPX8 in cancer are still being investigated.
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