Minichromosome Maintenance Complex Component 2 — it’s one of six highly conserved proteins (MCM2–MCM7) that form the MCM helicase complex, which is essential for DNA replication.
MCM2 is overexpressed in many cancers (breast, lung, colon, prostate, brain, etc.), and that overexpression correlates with:
-Increased cell proliferation
-Genomic instability
-Poor prognosis and lower survival rates
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