miR-101 is one of the best-established tumor-suppressor microRNAs in cancer biology. It acts as a master epigenetic and signaling regulator, and its loss is strongly linked to EMT, metastasis, cancer stemness, immune evasion, and therapy resistance across many tumor types.
-miR-101 strongly inhibits EMT
-miR-101 suppresses CSC traits
-suppresses EZH2
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