Similar to Mast/stem cell growth factor receptor precursor (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen); v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.
KIT protein is also known as the stem cell factor receptor (SCFR) or CD117. It is a type of receptor tyrosine kinase that binds to its ligand, stem cell factor (SCF). This interaction is crucial for various biological processes, including hematopoiesis (the formation of blood cells), melanogenesis (the formation of melanin in skin cells), and the development of certain types of immune cells.
In some cases, high KIT expression may be associated with a poorer prognosis. Targeted therapies that inhibit KIT signaling are being explored in clinical settings for cancers where KIT plays a role.
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