KLF4 (Kruppel-like factor 4) is a transcription factor that plays a significant role in various biological processes, including cell differentiation, proliferation, and apoptosis.
KLF4 has a complex role in cancer, acting as both a tumor suppressor and an oncogene depending on the specific cancer type and context.
In many cancers, KLF4 acts as a tumor suppressor, where its downregulation is associated with increased tumor growth, invasion, and poor prognosis. This is often due to its role in regulating genes involved in cell cycle control, differentiation, and apoptosis.
KLF4 levels, which plays an important role in stem cell formation.
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