A cytokine that plays a role in the immune response.
MIF is produced by various cell types, including macrophages, and can influence the tumor microenvironment. It can promote inflammation, which is often associated with tumor progression.
MIF has been shown to promote the proliferation and survival of cancer cells. It can activate signaling pathways that lead to increased cell growth and resistance to apoptosis (programmed cell death).
MIF levels in the blood or tumor tissue may correlate with disease progression or poor prognosis.
MIF is often overexpressed in several types of cancers, including breast, lung, colorectal, pancreatic, and gastric cancers.
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