RUNX1 is a gene that encodes a transcription factor involved in the regulation of hematopoiesis (the formation of blood cells) and is crucial for the development of various blood cell lineages. It plays a significant role in the differentiation and function of hematopoietic stem cells.
RUNX1 is often considered a tumor suppressor in hematopoietic cells. Loss of RUNX1 function can lead to uncontrolled cell proliferation and survival, contributing to cancer progression.
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