Regulatory T cells (Tregs) are a subset of T lymphocytes that play a crucial role in maintaining immune tolerance and preventing autoimmune diseases. They are characterized by the expression of specific markers, such as CD4, CD25, and the transcription factor FoxP3.
Tregs are often found in high numbers within the tumor microenvironment. Their presence can suppress anti-tumor immune responses, allowing cancer cells to evade immune detection and destruction. By inhibiting the activity of effector T cells and other immune components, Tregs can promote tumor growth and metastasis.
(Will delete Record if Target field = "Delete") Home