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tid Target Cancers General Effect on Target
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An enzyme that in humans is encoded by the AMACR gene.
AMACR is a valuable diagnostic marker because of its persistent and strong expression in case of needle biopsies.
(AMACR) is a mitochondrial and peroxisomal enzyme that is overexpressed in prostate cancer(PCa). AMACR is frequently used as a biomarker in prostate cancer diagnosis. Its expression is typically elevated in malignant prostate tissues compared to benign tissues. The overexpression of AMACR is associated with the presence of cancer and can aid in differentiating between cancerous and non-cancerous prostate tissues.
Other Cancers: In colorectal and breast cancers, AMACR expression has been associated with tumor progression and may serve as a prognostic marker. Elevated AMACR levels could indicate a more aggressive tumor phenotype, leading to worse survival rates.




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