Trx1 is useful for the early diagnosis of breast cancer or the early prediction prognosis of breast cancer, and therefore has a valuable use as a diagnostic marker and companion marker to CEA and CA15-3 for breast cancer.
- Cytosolic thioredoxin (TRX-1) vs mitochondrial thioredoxin (TRX-2).
The Trx1 level of patients with other types of cancer was close to that of women without cancer, indicating that the blood Trx1 level has potential to could discern BC from other types of cancer.
Many tumor types, including lung, breast, colon, and prostate cancers, have shown elevated levels of TRX.
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