The COMP gene (Cartilage Oligomeric Matrix Protein) is a gene that encodes a protein involved in the formation and maintenance of cartilage. While COMP is not typically considered a tumor suppressor gene or an oncogene, mutations in the COMP gene have been associated with various types of cancer.
COMP is overexpressed in certain types of cancer, including: Osteosarcoma (bone cancer), Chondrosarcoma (cartilage cancer), Breast, Lung, CRC.
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