CDKN2A is a vital tumor suppressor gene that plays a key role in regulating the cell cycle and maintaining genomic stability.
CDKN2A (Cyclin-Dependent Kinase Inhibitor 2A) is a crucial tumor suppressor gene that encodes two important proteins, p16INK4a and p14ARF, which play significant roles in regulating the cell cycle and cellular responses to stress.
Its inactivation is a common event in many cancers, contributing to tumorigenesis and disease progression.
The status of CDKN2A can serve as a prognostic marker in various cancers. Loss of CDKN2A expression is often associated with poor prognosis and more aggressive disease.
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