Centrosome Clustering in Cancer Cells: To counteract the effects of centrosome amplification, cancer cells often employ centrosome clustering. By clustering multiple centrosomes, cancer cells can form a more stable bipolar spindle, which helps to maintain some level of proper chromosome segregation despite the presence of extra centrosomes. However, this is a temporary solution and does not fully resolve the underlying issues of genomic instability.
Many cancer cells exhibit centrosome amplification, where cells have more than two centrosomes.
(Will delete Record if Target field = "Delete") Home