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tid Target Cancers General Effect on Target
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Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such are necessary for T cell-mediated cancer immunity.
DC subsets are often classified by developmental origin as conventional DC [including type 1 conventional DC (cDC1) and type 2 conventional DC (cDC2)], monocyte-derived DC (MoDC), plasmacytoid DC (pDC) as well as the emerging appreciation of a population, termed DC3.

Dendritic cells play a vital role in the immune response to cancer, and their presence and functional status in the tumor microenvironment can significantly impact prognosis. Generally, a higher density of activated dendritic cells is associated with better clinical outcomes across various cancer types.




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